Publication Name	World Journal of Cardiology
Manuscript ID	7993
Country	United Kingdom

Received	2013-12-15 18:14
Peer-Review Started	2013-12-16 08:25
To Make the First Decision	2014-01-08 14:38
Return for Revision	2014-01-09 11:12
Revised
Second Decision	2014-05-08 17:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-08 17:51
Articles in Press	2014-05-23 09:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-06-25 08:58
Publish the Manuscript Online	2014-06-26 14:40

ISSN	1949-8462 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Systematic Reviews
Article Title	Thrapeutic equivalence in the treatment of hypertension: Can lercanidipine and nifedipine GITS be considered to be interchangeable?
Manuscript Source	Invited Manuscript
All Author List	Henry L Elliott and Peter A Meredith
Funding Agency and Grant Number
Corresponding Author	Peter A Meredith, Senior University Teacher, Department of Medicine and Therapeutics, University of Glasgow, The Western Infirmary, 378 Sauchiehall Street, Glasgow G11 6NT, United Kingdom. peter.meredith@glasgow.ac.uk
Key Words	Nifedipine GITS; Lercanidipine; Therapeutic equivalence
Core Tip	Even in this time of “evidence-based medicine”, there is a widespread presumption of “class effects” in therapeutic practice including that for antihypertensive drug treatments. Thus, guidelines tend to recommend treatment not with specific agents but with groups or classes such as “calcium channel blockers” on the presumption of the therapeutic equivalence or inter-changeability of different agents. This literature review focuses attention on the apparent therapeutic advantage of lercanidipine over nifedipine GITS on the basis of a lower incidence of the adverse effect of peripheral (ankle) oedema. Overall, however, the balance of evidence of efficacy favours nifedipine GITS.
Publish Date	2014-06-26 14:40
Citation	Elliott HL, Meredith PA. Thrapeutic equivalence in the treatment of hypertension: Can lercanidipine and nifedipine GITS be considered to be interchangeable? World J Cardiol 2014; 6(6): 507-513
URL	http://www.wjgnet.com/1949-8462/full/ v6/i6/507.htm
DOI	http://dx.doi.org/10.4330/wjc.v6.i6.507

Full Article (PDF)	WJC-6-507.pdf
Full Article (Word)	WJC-6-507.doc
Manuscript File	7993-Review.docx
Answering Reviewers	7993-Answering reviewers.pdf
Copyright License Agreement	7993-Copyright assignment.pdf
Peer-review Report	7993-Peer review(s).pdf
Scientific Editor Work List	7993-Scientific editor work list.pdf