| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Drug-induced sarcoidosis-like reaction three months after BNT162b2 mRNA COVID-19 vaccination: A case report and review of literature
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Soo Ryang Kim, Soo Ki Kim, Takako Fujii, Hisato Kobayashi, Toyokazu Okuda, Takanobu Hayakumo, Atsushi Nakai, Yumi Fujii, Ryuji Suzuki, Noriko Sasase, Aya Otani, Yu-ichiro Koma, Motoko Sasaki, Tsutomu Kumabe and Osamu Nakashima |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Soo Ki Kim, MD, PhD, Director, Director, Doctor, Doctor, Department of Gastroenterology, Kobe Asahi Hospital, 3-5-25, Bououji-cho, Nagata-ku, Kobe, Kobe 6530801, Hyogo, Japan. kinggold@kobe-asahi-hp.com |
| Key Words |
Drug-induced sarcoidosis-like reaction; BNT162b2 mRNA COVID-19 vaccine; Noncaseating granuloma; Ethoxybenzyl diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging; Th1/Th2 profile; Case report |
| Core Tip |
We describe a case of drug-induced sarcoidosis-like reaction (DISR) a noncaseating hepatic sarcoid-like epithelioid granuloma (HSEG). Histopathological analysis disclosed, characteristic spindle-shaped epithelioid cells harboring Langhans-type multinucleated giant cells. Two months and 5 mo after the third BNT162b2 messenger RNA (mRNA) coronavirus disease 2019 vaccination, the occurrence of HSEG was not confirmed before rechallenging the drug-induced DISR by the third mRNA vaccination. |
| Publish Date |
2023-01-05 03:12 |
| Citation |
Kim SR, Kim SK, Fujii T, Kobayashi H, Okuda T, Hayakumo T, Nakai A, Fujii Y, Suzuki R, Sasase N, Otani A, Koma YI, Sasaki M, Kumabe T, Nakashima O. Drug induced sarcoidosis-like reaction three months after BNT162b2 mRNA COVID-19 vaccination: A case report and review of literature. World J Clin Cases 2023; 11(1): 177-186 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i1/177.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i1.177 |
