Publication Name	World Journal of Clinical Cases
Manuscript ID	79983
Country	China

Received	2022-10-13 03:46
Peer-Review Started	2022-10-13 03:50
To Make the First Decision
Return for Revision	2022-11-30 07:43
Revised	2022-12-29 13:44
Second Decision	2023-01-12 03:12
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-01-12 08:36
Articles in Press	2023-01-12 08:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-01-28 12:48
Publish the Manuscript Online	2023-02-06 06:38

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Immunology
Manuscript Type	Case Report
Article Title	Unusual presentation of systemic lupus erythematosus as hemophagocytic lymphohistiocytosis in a female patient: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Li-Yuan Peng, Jing-Bo Liu, Hou-Juan Zuo and Gui-Fen Shen
ORCID	Author(s) ORCID Number Li-Yuan Peng http://orcid.org/0000-0002-0813-1449 Gui-Fen Shen http://orcid.org/0000-0002-3040-4482
Funding Agency and Grant Number
Corresponding Author	Gui-Fen Shen, MD, Doctor, Doctor, Department of Rheumatology and Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan 430030, Hubei Province, China. guifenshen@126.com
Key Words	Hemophagocytic lymphohistiocytosis; Systemic lupus erythematosus; Autoimmune abnormalities; Case report
Core Tip	Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening disorder, including primary HLH and secondary HLH (sHLH). We report a rare case of a 36-year-old female manifested with sHLH on background with systemic lupus erythematosus (SLE) and related with decreased activity of natural killer cells according to whole exon gene sequencing. Our study expanded the thoughts on the diagnosis and treatment of HLH in SLE patients.
Publish Date	2023-02-06 06:38
Citation	Peng LY, Liu JB, Zuo HJ, Shen GF. Unusual presentation of systemic lupus erythematosus as hemophagocytic lymphohistiocytosis in a female patient: A case report. World J Clin Cases 2023; 11(4): 909-917
URL	https://www.wjgnet.com/2307-8960/full/v11/i4/909.htm
DOI	https://dx.doi.org/10.12998/wjcc.v11.i4.909

Full Article (PDF)	WJCC-11-909.pdf
Full Article (Word)	WJCC-11-909.docx
Manuscript File	79983_Auto_Edited-LJH-JLW.docx
Answering Reviewers	79983-Answering reviewers.pdf
Audio Core Tip	79983-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	79983-Conflict-of-interest statement.pdf
Copyright License Agreement	79983-Copyright license agreement.pdf
Signed Consent for Treatment Form(s) or Document(s)	79983-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	79983-Language certificate.pdf
Supplementary Material	79983-Supplementary material.pdf
Peer-review Report	79983-Peer-review(s).pdf
Scientific Misconduct Check	79983-Bing-Liu JH-2.jpg
Scientific Misconduct Check	79983-CrossCheck.jpg
Scientific Editor Work List	79983-Scientific editor work list.pdf
CrossCheck Report	79983-CrossCheck report.pdf