Publication Name	World Journal of Medical Genetics
Manuscript ID	8003
Country	Spain

Received	2013-12-11 09:45
Peer-Review Started	2013-12-11 17:45
To Make the First Decision	2014-01-16 08:13
Return for Revision	2014-01-17 13:12
Revised	2014-01-23 23:03
Second Decision	2014-04-03 10:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-03 11:00
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-27 18:57
Publish the Manuscript Online	2014-05-28 15:12

ISSN	2220-3184 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Topic Highlights
Article Title	Structure-function relationship in viral RNA genomes: The case of hepatitis C virus
Manuscript Source	Invited Manuscript
All Author List	Cristina Romero-López and Alfredo Berzal-Herranz
Funding Agency and Grant Number	Funding Agency Grant Number Spanish Ministry of Economy and Competitiveness BFU2012-31213 Junta de Andalucía CVI-7430 FEDER funds from the EU
Corresponding Author	Cristina Romero-López, PhD, Instituto de Parasitología y Biomedicina López-Neyra, IPBLN-CSIC, PTS Granada, Avda. del Conocimiento s/n, Armilla, 18016 Granada, Spain. cristina_romero@ipb.csic.es
Key Words	Functional RNA domain; Cis-acting replicating element; Hepatitis C virus; Internal ribosome entry site; RNA-RNA interaction; Untranslatable region
Core Tip	This review summarizes the main aspects of structurally conserved genomic RNA elements in the hepatitis C virus (HCV) genome and their role in the viral cycle. The genome of RNA viruses is a dynamic genetic entity endorsed with an information storage system defined by highly conserved, complex structural units, termed functional RNA domains. The genome of HCV contains several well-studied functional RNA domains that control essential viral processes, as well as transitions between them, by recruiting protein factors and also by establishing a complex, direct and long-range RNA-RNA interaction network.
Publish Date	2014-05-28 15:12
Citation	Romero-López C, Berzal-Herranz A. Structure-function relationship in viral RNA genomes: The case of hepatitis C virus. World J Med Genet 2014; 4(2): 6-18
URL	http://www.wjgnet.com/2220-3184/full/v4/i2/6.htm
DOI	http://dx.doi.org/10.5496/wjmg.v4.i2.6

Full Article (PDF)	WJMG-4-6.pdf
Full Article (Word)	WJMG-4-6.doc
Manuscript File	8003-Review.doc
Answering Reviewers	8003-Answering reviewers.pdf
Copyright License Agreement	8003-Copyright assignment.pdf
Peer-review Report	8003-Peer review(s).pdf
Scientific Editor Work List	8003-Scientific editor work list.doc