Publication Name	World Journal of Gastroenterology
Manuscript ID	8004
Country	Italy

Received	2013-12-11 09:48
Peer-Review Started	2013-12-11 17:48
First Decision by Editorial Office Director
Return for Revision	2014-01-20 18:30
Revised	2014-02-07 22:19
Publication Fee Transferred
Second Decision by Editor	2014-03-10 15:11
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-03-10 16:54
Articles in Press	2014-05-23 10:28
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-06-22 16:27
Publish the Manuscript Online	2014-07-03 15:30

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Hepatocellular carcinoma treated by conventional transarterial chemoembolization in field-practice: Serum sodium predicts survival
Manuscript Source	Unsolicited Manuscript
All Author List	Marco Biolato, Luca Miele, Vittoria Vero, Simona Racco, Carmine Di Stasi, Roberto Iezzi, Andrea Zanché, Maurizio Pompili, Gian Ludovico Rapaccini, Giuseppe La Torre, Antonio Gasbarrini and Antonio Grieco
Funding Agency and Grant Number
Corresponding Author	Antonio Grieco, MD, Professor of Medicine, Hepatology Unit, Department of Internal Medicine, Policlinico Gemelli Hospital and Catholic University of the Sacred Heart, Largo Agostino Gemelli n 8, 00168 Rome, Italy. agrieco@rm.unicatt.it
Key Words	Liver cancer; Sorafenib; Hyponatremia; Model for end-stage liver disease sodium; Chemoembolization
Core Tip	This work describes, in a retrospective cohort of 270 patients with hepatocellular carcinoma (HCC) treated with conventional transarterial chemoembolization (TACE) at our institution, the prognostic role of baseline clinical, biochemical and radiological characteristics of patients. Besides well-known prognostic parameters like portal vein thrombosis, nodule diameter and number of lesions, this study underlines the independent prognostic role of serum sodium, a well-known prognostic parameter in the field of liver cirrhosis, but less investigated in the field of hepatocellular carcinoma. Our study is the first to document the prognostic role of serum sodium in patients with HCC treated with TACE in a Western center.
Publish Date	2014-07-03 15:30
Citation	Biolato M, Miele L, Vero V, Racco S, Di Stasi C, Iezzi R, Zanché A, Pompili M, Rapaccini GL, La Torre G, Gasbarrini A, Grieco A. Hepatocellular carcinoma treated by conventional transarterial chemoembolization in field-practice: Serum sodium predicts survival. World J Gastroenterol 2014; 20(25): 8158-8165
URL	http://www.wjgnet.com/1007-9327/full/v20/i25/8158.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i25.8158

Full Article (PDF)	WJG-20-8158.pdf
Full Article (Word)	WJG-20-8158.doc
Manuscript File	8004-Review.doc
Answering Reviewers	8004-Answering reviewers.pdf
Copyright License Agreement	8004-Copyright_Assignment.pdf
Non-Native Speakers of English Editing Certificate	8004-Language certificate.pdf
Peer-review Report	8004-Peer review(s).pdf