Publication Name	World Journal of Gastroenterology
Manuscript ID	80043
Country	Japan

Received	2022-09-15 02:06
Peer-Review Started	2022-09-15 02:07
To Make the First Decision
Return for Revision	2022-10-30 20:03
Revised	2022-11-07 15:42
Second Decision	2022-12-02 03:08
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-12-05 17:53
Articles in Press	2022-12-05 17:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-12-21 00:00
Publish the Manuscript Online	2022-12-27 10:06

ISSN	1007-9327 (print) and 2219-2840 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Confusion and prospects for carcinogenesis of gastric adenoma and dysplasia: What is the correct answer currently?
Manuscript Source	Invited Manuscript
All Author List	Shinichi Kinami, Sohsuke Yamada and Hiroyuki Takamura
ORCID	Author(s) ORCID Number Shinichi Kinami http://orcid.org/0000-0001-9867-3120 Sohsuke Yamada http://orcid.org/0000-0003-2662-0024 Hiroyuki Takamura http://orcid.org/0000-0001-9351-1309
Funding Agency and Grant Number
Corresponding Author	Shinichi Kinami, MD, PhD, Professor, Department of Surgical Oncology, Kanazawa Medical University, 1-1 Daigaku, Uchinada-machi, kahoku-gun 920-0293, Ishikawa, Japan. kinami@kanazawa-med.ac.jp
Key Words	Gastric adenoma; Low-grade dysplasia; High-grade dysplasia; Intramucosal carcinoma; Submucosal carcinoma; Endoscopic submucosal dissection
Core Tip	Gastric carcinogenesis occurs mostly de novo. Superficial gastric tumors can be roughly divided into the APC mutation type and the TP53 mutation type, which are mutually exclusive. APC-type tumors have low malignancy and develop into low-grade dysplasia, whereas TP53-type tumors have high malignancy and are considered cancerous even if they are small. For lesions diagnosed as category 3 or 4 in the Vienna classification system, endoscopic submucosal dissection and staging should be performed. If the tumor is diagnosed with lymphovascular or submucosal invasion, additional surgical treatment of gastrectomy with lymph node dissection is required.
Publish Date	2022-12-27 10:06
Citation	Kinami S, Yamada S, Takamura H. Confusion and prospects for carcinogenesis of gastric adenoma and dysplasia: What is the correct answer currently? World J Gastroenterol 2022; 28(48): 6900-6908
URL	https://www.wjgnet.com/1007-9327/full/v28/i48/6900.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i48.6900

Full Article (PDF)	WJG-28-6900.pdf
Full Article (Word)	WJG-28-6900.docx
Manuscript File	80043_Auto_Edited-LM.docx
Answering Reviewers	80043-Answering reviewers.pdf
Audio Core Tip	80043-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	80043-Conflict-of-interest statement.pdf
Copyright License Agreement	80043-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	80043-Language certificate.pdf
Peer-review Report	80043-Peer-review(s).pdf
Scientific Misconduct Check	80043-Bing-Chen YL-2.png
Scientific Editor Work List	80043-Scientific editor work list.pdf
CrossCheck Report	80043-CrossCheck report.pdf