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8/22/2014 5:28:00 PM | Browse: 1091 | Download: 979
Publication Name World Journal of Clinical Oncology
Manuscript ID 8006
Country/Territory Argentina
Received
2013-12-11 09:58
Peer-Review Started
2013-12-11 18:13
To Make the First Decision
2014-01-16 08:13
Return for Revision
2014-01-17 13:14
Revised
2014-01-21 04:08
Second Decision
2014-04-03 10:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-04-03 11:00
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-07-22 17:25
Publish the Manuscript Online
2014-08-01 16:16
ISSN 2218-4333 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Topic Highlights
Article Title Alcohol drinking and mammary cancer: Pathogenesis and potential dietary preventive alternatives
Manuscript Source Invited Manuscript
All Author List Gerardo Daniel Castro and José A Castro
Funding Agency and Grant Number
Corresponding Author José A Castro, PhD, Professor of Toxicology, Centro de Investigaciones Toxicológicas, CITEDEF, Juan B. de La Salle 4397, B1603ALO Villa Martelli, Province of Buenos Aires, Argentina. jcastro@unsam.edu.ar
Key Words Alcohol; Ethanol; Acetaldehyde; Free radicals; Mammary cancer; Oxidative stress; Estrogens; Polyphenols
Core Tip Excessive alcohol drinking of any type of alcoholic beverage is known to linearly increase the risk of breast cancer. The precise mechanism involved to produce this effect is still far from being established. In this review we introduce our present working hypothesis integrating the participation in cancer initiation and promotion of: in situ accumulation of the acetaldehyde metabolite, the local promotion of oxidative stress and the effects of the increased levels of estrogen occurring during alcohol drinking. Some potential preventive alternatives were also analyzed.
Publish Date 2014-08-01 16:16
Citation Castro GD, Castro JA. Alcohol drinking and mammary cancer: Pathogenesis and potential dietary preventive alternatives. World J Clin Oncol 2014; 5(4): 713-729
URL http://www.wjgnet.com/2218-4333/full/v5/i4/713.htm
DOI http://dx.doi.org/10.5306/wjco.v5.i4.713
Full Article (PDF) WJCO-5-713.pdf
Full Article (Word) WJCO-5-713.doc
Manuscript File 8006-Review.doc
Answering Reviewers 8006-Answering reviewers.pdf
Copyright License Agreement 8006-Copyright assignment.pdf
Peer-review Report 8006-Peer review(s).pdf
Scientific Editor Work List 8006-Scientific editor work list.doc