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Articles Published Processes
2/14/2023 12:24:40 PM | Browse: 222 | Download: 654
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Received |
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2022-09-16 02:30 |
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Peer-Review Started |
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2022-09-16 02:35 |
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To Make the First Decision |
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Return for Revision |
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2022-11-18 08:10 |
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Revised |
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2022-11-26 10:41 |
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Second Decision |
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2022-12-20 08:10 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-12-21 02:44 |
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Articles in Press |
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2022-12-21 02:44 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-02-07 11:12 |
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Publish the Manuscript Online |
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2023-02-14 12:24 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemical Research Methods |
| Manuscript Type |
Basic Study |
| Article Title |
Protective effect of liraglutide on the myocardium of type 2 diabetic rats by inhibiting polyadenosine diphosphate-ribose polymerase-1
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Dong-Dong Xue, Xiang Zhang, De-Wei Li, Yan-Lan Yang and Jing-Jin Liu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Shanxi Provincial Natural Science Foundation |
201701D121159 |
| Shanxi Provincial Health and Family Planning Commission |
2014016 |
| Health Commission of Shanxi Province |
2019020 |
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| Corresponding Author |
Jing-Jin Liu, MD, Technician, Department of Endocrinology, Shanxi Provincial People's Hospital , No. 29 Shuangta Street , Taiyuan 030012, Shanxi Province, China. liumeng237237@163.com |
| Key Words |
Liraglutide; animal models; Type 2 diabetic rats; Polyadenosine diphosphate-ribose polymerase-1; Haematoxylin and eosin staining; Immunohistochemistry |
| Core Tip |
Low-dose streptozotocin combined with a high-glucose and high-fat diet can successfully establish a rat model of type 2 diabetes mellitus. After 4 wk of continuous feeding, myocardial injury can occur, which is consistent with diabetic cardiomyopathy. Liraglutide reduced the body weight of type 2 diabetic rats and significantly improved the fasting blood glucose and lipid profile in a dose-dependent manner. Liraglutide may improve myocardial injury in type 2 diabetic rats by inhibiting the expression of myocardial polyadenosine diphosphate-ribose polymerase-1 in a dose-dependent manner. |
| Publish Date |
2023-02-14 12:24 |
| Citation |
Xue DD, Zhang X, Li DW, Yang YL, Liu JJ. Protective effect of liraglutide on the myocardium of type 2 diabetic rats by inhibiting polyadenosine diphosphate-ribose polymerase-1. World J Diabetes 2023; 14(2): 110-119 |
| URL |
https://www.wjgnet.com/1948-9358/full/v14/i2/110.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v14.i2.110 |
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