| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Immunology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Antibody and complement levels in patients with hypersplenism associated with cirrhotic portal hypertension and therapeutic principles
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Kun Zhang, Min Zeng, Ye-Juan Li, Hong-Fei Wu, Jin-Cai Wu, Zhen-Sheng Zhang, Jin-Fang Zheng and Yun-Fu Lv |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Hainan Provincial Department of Science and Technology |
Qiongke[2020]256 |
|
| Corresponding Author |
Yun-Fu Lv, Doctor, MD, PhD, Academic Research, Chief Doctor, Professor, Research Scientist, Surgeon, Department of General Surgery, Hainan General Hospital, No. 19 Xiuhua Road, Xiuyin District, Haikou 570311, Hainan Province, China. yunfu_lv@126.com |
| Key Words |
Hypersplenism associated with cirrhotic portal hypertension; Complement; Treatment; Hepatitis; B-immunoglobulin |
| Core Tip |
Patients with cirrhotic portal hypertension and hypersplenism are clinically common. The spleen is an important immune organ, but studies on antibody and complement levels in patients are scarce. This study found that IgA and IgG levels increased and complement levels decreased in our patient population compared to the healthy controls. These findings indicate liver damage, supporting the need for anti-viral treatment in these patients. |
| Publish Date |
2022-12-26 18:23 |
| Citation |
Zhang K, Zeng M, Li YJ, Wu HF, Wu JC, Zhang ZS, Zheng JF, Lv YF. Antibody and complement levels in patients with hypersplenism associated with cirrhotic portal hypertension and therapeutic principles. World J Clin Cases 2022; 10(36): 13208-13215 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i36/13208.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i36.13208 |
