Publication Name	World Journal of Gastroenterology
Manuscript ID	8032
Country	China

Received	2013-12-12 16:19
Peer-Review Started	2013-12-12 18:30
To Make the First Decision	2013-12-26 11:14
Return for Revision	2013-12-27 13:51
Revised	2014-01-05 16:09
Second Decision	2014-04-03 10:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-04-03 11:31
Articles in Press	2014-05-23 09:19
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-04-18 19:25
Typeset the Manuscript	2014-05-23 13:23
Publish the Manuscript Online	2014-06-16 16:19

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Expression of gastrointestinal nesfatin-1 and gastric emptying in ventromedial hypothalamic nucleus- and ventrolateral hypothalamic nucleus-lesioned rats
Manuscript Source	Unsolicited Manuscript
All Author List	Zi-Bin Tian, Run-Jun Deng, Gui-Rong Sun, Liang-Zhou Wei, Xin-Juan Kong, Xue-Li Ding, Xue Jing, Cui-Ping Zhang and Yin-Lin Ge
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81070305 Natural Science Foundation of Shandong Province zr2010hm066
Corresponding Author	Zi-Bin Tian, MD, Department of Gastroenterology, Affiliated Hospital of Medical College of Qingdao University, 16 Jiangsu Road, Qingdao 266003, Shandong Province, China. tianzb@qdumh.qd.sd.cn
Key Words	Nucleobindin; Nesfatin-1; Gastrointestinal tract; Gastric emptying; Ventromedial hypothalamic nucleus; Hyperphagia; Obesity; Anorexia
Core Tip	We report that nesfatin-1 level in the stomach and duodenum is positively correlated with body mass. To our knowledge, this is the first time to detect the nesfatin-1 level in the duodenum, small intestine and colon with traditional obese and lean subjects induced by nuclei lesions. Additionally, the data of gastric nefatin-1 expression are an objective supplement to the previous report. Notably, we also show a positive relationship between gastric emptying and body mass. Further, it is possible that the expression level of gastrointestinal nesfatin-1 may be used to diagnose the gastric mobility disorder and metabolism disturbance.
Publish Date	2014-06-16 16:19
Citation	Tian ZB, Deng RJ, Sun GR, Wei LZ, Kong XJ, Ding XL, Jing X, Zhang CP, Ge YL. Expression of gastrointestinal nesfatin-1 and gastric emptying in ventromedial hypothalamic nucleus- and ventrolateral hypothalamic nucleus-lesioned rats. World J Gastroenterol 2014; 20(22): 6897-6905
URL	http://www.wjgnet.com/1007-9327/full/v20/i22/6897.htm
DOI	10.3748/wjg.v20.i22.6897

Full Article (PDF)	WJG-20-6897.pdf
Full Article (Word)	WJG-20-6897.doc
Manuscript File	8032-Review.doc
Answering Reviewers	8032-Answering reviewers.pdf
Copyright License Agreement	8032-Copyright assignment.pdf
Peer-review Report	8032-Peer review(s).pdf
Scientific Editor Work List	8032-Scientific editor work list.doc