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Articles Published Processes
8/26/2014 3:51:00 PM | Browse: 1107 | Download: 1178
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Received |
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2013-12-12 16:19 |
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Peer-Review Started |
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2013-12-12 18:30 |
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To Make the First Decision |
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2013-12-26 11:14 |
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Return for Revision |
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2013-12-27 13:51 |
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Revised |
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2014-01-05 16:09 |
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Second Decision |
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2014-04-03 10:07 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-04-03 11:31 |
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Articles in Press |
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2014-05-23 09:19 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-04-18 19:25 |
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Typeset the Manuscript |
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2014-05-23 13:23 |
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Publish the Manuscript Online |
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2014-06-16 16:19 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Autobiography |
Article Title |
Expression of gastrointestinal nesfatin-1 and gastric emptying in ventromedial hypothalamic nucleus- and ventrolateral hypothalamic nucleus-lesioned rats
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Zi-Bin Tian, Run-Jun Deng, Gui-Rong Sun, Liang-Zhou Wei, Xin-Juan Kong, Xue-Li Ding, Xue Jing, Cui-Ping Zhang and Yin-Lin Ge |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
81070305 |
Natural Science Foundation of Shandong Province |
zr2010hm066 |
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Corresponding Author |
Zi-Bin Tian, MD, Department of Gastroenterology, Affiliated Hospital of Medical College of Qingdao University, 16 Jiangsu Road, Qingdao 266003, Shandong Province, China. tianzb@qdumh.qd.sd.cn |
Key Words |
Nucleobindin; Nesfatin-1; Gastrointestinal tract; Gastric emptying; Ventromedial hypothalamic nucleus; Hyperphagia; Obesity; Anorexia |
Core Tip |
We report that nesfatin-1 level in the stomach and duodenum is positively correlated with body mass. To our knowledge, this is the first time to detect the nesfatin-1 level in the duodenum, small intestine and colon with traditional obese and lean subjects induced by nuclei lesions. Additionally, the data of gastric nefatin-1 expression are an objective supplement to the previous report. Notably, we also show a positive relationship between gastric emptying and body mass. Further, it is possible that the expression level of gastrointestinal nesfatin-1 may be used to diagnose the gastric mobility disorder and metabolism disturbance. |
Publish Date |
2014-06-16 16:19 |
Citation |
Tian ZB, Deng RJ, Sun GR, Wei LZ, Kong XJ, Ding XL, Jing X, Zhang CP, Ge YL. Expression of gastrointestinal nesfatin-1 and gastric emptying in ventromedial hypothalamic nucleus- and ventrolateral hypothalamic nucleus-lesioned rats. World J Gastroenterol 2014; 20(22): 6897-6905 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i22/6897.htm |
DOI |
10.3748/wjg.v20.i22.6897 |
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