Publication Name	World Journal of Orthopedics
Manuscript ID	80416
Country	Greece

Received	2022-09-26 21:59
Peer-Review Started	2022-09-26 22:02
To Make the First Decision
Return for Revision	2022-10-21 02:48
Revised	2022-11-04 19:40
Second Decision	2022-12-07 03:23
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-12-08 17:24
Articles in Press	2022-12-08 17:24
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-12-25 12:37
Typeset the Manuscript	2023-01-11 01:41
Publish the Manuscript Online	2023-01-13 09:12

ISSN	2218-5836 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Minireviews
Article Title	Polydactyly: Clinical and molecular manifestations
Manuscript Source	Invited Manuscript
All Author List	Zisis Kyriazis, Panagoula Kollia, Ioanna Grivea, Nikolaos Stefanou, Sotirios Sotiriou and Zoe H Dailiana
ORCID	Author(s) ORCID Number Zisis Kyriazis http://orcid.org/0000-0003-2465-8774 Panagoula Kollia http://orcid.org/0000-0002-0635-3996 Ioanna Grivea http://orcid.org/0000-0002-9221-5628 Nikolaos Stefanou http://orcid.org/0000-0002-6784-6022 Sotirios Sotiriou http://orcid.org/0000-0002-9466-6086 Zoe H Dailiana http://orcid.org/0000-0003-3890-0832
Funding Agency and Grant Number
Corresponding Author	Zoe H Dailiana, MD, PhD, Professor, Surgeon, Department of Orthopaedic Surgery, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Larissa 41500, Greece. dailiana@med.uth.gr
Key Words	Polydactyly; Gene; Syndromic; Non-syndromic; Preaxial; Postaxial
Core Tip	The molecular basis of hand and foot polydactyly, syndromic or non- syndromic, is diverse. There are several phenotypes of the disorder which are correlated to a specific molecular profile and other whose molecular basis is still unclear. We summarize and provide an overview of gene mutations that cause hand and foot polydactyly as an isolated disorder or as part of a syndrome and present the clinical manifestations that they cause.
Publish Date	2023-01-13 09:12
Citation	Kyriazis Z, Kollia P, Grivea I, Stefanou N, Sotiriou S, Dailiana ZH. Polydactyly: Clinical and molecular manifestations. World J Orthop 2023; 14(1): 13-22
URL	https://www.wjgnet.com/2218-5836/full/v14/i1/13.htm
DOI	https://dx.doi.org/10.5312/wjo.v14.i1.13

Full Article (PDF)	WJO-14-13.pdf
Full Article (Word)	WJO-14-13.docx
Manuscript File	80416_Auto_Edited-LM_WangTQ.docx
Answering Reviewers	80416-Answering reviewers.pdf
Audio Core Tip	80416-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	80416-Conflict-of-interest statement.pdf
Copyright License Agreement	80416-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	80416-Language certificate.pdf
Peer-review Report	80416-Peer-review(s).pdf
Scientific Misconduct Check	80416-Bing-Chang KL-2.png
Scientific Editor Work List	80416-Scientific editor work list.pdf
CrossCheck Report	80416-CrossCheck report.pdf