ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Study |
Article Title |
Hepatobiliary system and intestinal injury in new coronavirus infection (COVID-19): A retrospective study
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Manuscript Source |
Invited Manuscript |
All Author List |
Konstantin V Kozlov, Konstantin V Zhdanov, Anna K Ratnikova, Vyacheslav A Ratnikov, Artem V Tishkov, Vladimir Grinevich, Yuriy A Kravchuk, Panteley I Miklush, Polina O Nikiforova, Vera V Gordienko, Alexander F Popov and Boris G Andryukov |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Vera V Gordienko, MD, Doctor, Teacher, Department of Infection Disease, Military Medical Academy named after SM. Kirov, No. 6 Lebedeva Street, Saint-Petersburg 194044, Russia. ivanovavmeda@gmail.com |
Key Words |
Novel coronavirus infection; COVID-19; SARS-CoV-2; Zonulin; Faecal calprotectin; Microbiota |
Core Tip |
The clinical course of coronavirus disease 19 (COVID-19) was studied, and the clinical and biochemical features, manifestations of systemic inflammation, and intestinal microbiome changes in patients with mild and moderate severity were identified. Intestinal permeability characteristics against the background of COVID-19 were evaluated by measuring levels of proinflammatory cytokines, insulin, faecal calprotectin, and zonulin. This study highlights the role of intestinal permeability and microbiota as the main drivers of gastroenterological manifestations and increased COVID-19 severity. |
Publish Date |
2023-03-30 13:19 |
Citation |
Kozlov KV, Zhdanov KV, Ratnikova AK, Ratnikov VA, Tishkov AV, Grinevich V, Kravchuk YA, Miklush PI, Nikiforova PO, Gordienko VV, Popov AF, Andryukov BG. Hepatobiliary system and intestinal injury in new coronavirus infection (COVID -19): A retrospective study. World J Clin Cases 2023; 11(10): 2226-2236 |
URL |
https://www.wjgnet.com/2307-8960/full/v11/i10/2226.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v11.i10.2226 |