| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Completion of 6-mo isoniazid preventive treatment among eligible under six children: A cross-sectional study, Lagos, Nigeria
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Victor Abiola Adepoju, Ademola Adelekan, Aderonke Agbaje, Femi Quaitey, Tobi Ademola-Kay, Ann Uduak Udoekpo and Olusola Daniel Sokoya |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Victor Abiola Adepoju, MBChB, MSc, Doctor, Senior Editor, HIV and Infectious Diseases, Jhpiego Nigeria, Plot 971, Rueben Okoya Crescent, Wuye, Abuja, Nigeria, Federal Capital Territory, Abuja 900918, Abuja, Nigeria. schrodinga05@yahoo.com |
| Key Words |
Isoniazid; Child; Tuberculosis; Treatment Outcome; Completion; Latent tuberculosis; Dosage |
| Core Tip |
Isoniazid (INH) completion rate among children in Nigeria was suboptimal in this programmatic cohort. The chi-square analysis revealed that age, gender, and type of facility were not determinants of the treatment completion of INH recorded among eligible children initiated in Lagos, Nigeria. The huge drop-offs in the first 2 mo of INH calls for innovative strategies such as the use of 60-day INH calendar that would facilitate reminder and early engagement of children on INH and their caregivers in care and across the entire period of treatment. Targeted interventions such as community initiation and monitoring of INH by healthcare workers, and rapid scale up of shorter tuberculosis preventive therapy regimen are needed to address these drop-offs along the childhood INH cascade. Future studies should therefore qualitatively explore the reasons why some children did not complete the INH. |
| Publish Date |
2023-01-05 03:12 |
| Citation |
Adepoju VA, Adelekan A, Agbaje A, Quaitey F, Ademola-Kay T, Udoekpo AU, Sokoya OD. Completion of 6-mo isoniazid preventive treatment among eligible under six children: A cross-sectional study, Lagos, Nigeria. World J Clin Cases 2023; 11(1): 104-115 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i1/104.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i1.104 |
