Publication Name	World Journal of Nephrology
Manuscript ID	80913
Country	Argentina

Received	2022-10-18 13:19
Peer-Review Started	2022-10-18 13:21
To Make the First Decision
Return for Revision	2022-12-26 09:21
Revised	2023-01-18 18:28
Second Decision	2023-03-17 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-03-17 07:27
Articles in Press	2023-03-17 07:27
Publication Fee Transferred
Edit the Manuscript by Language Editor	2023-03-14 03:28
Typeset the Manuscript	2023-03-20 04:29
Publish the Manuscript Online	2023-03-21 06:38

ISSN	2220-6124 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Urology & Nephrology
Manuscript Type	Minireviews
Article Title	Kidney stone matrix proteins: Their role in stone formation
Manuscript Source	Invited Manuscript
All Author List	Armando Luis Negri and Francisco Rodolfo Spivacow
ORCID	Author(s) ORCID Number Armando Luis Negri http://orcid.org/0000-0003-1243-6568 Francisco Rodolfo Spivacow http://orcid.org/0000-0001-7048-3317
Funding Agency and Grant Number
Corresponding Author	Armando Luis Negri, FACP, MD, Academic Editor, Professor, Department of Physiology and Biophysics, Instituto de Investigaciones Metabólicas, Libertad 836 1 Piso, Buenos Aires, 1012, Buenos Aires 1012, Argentina. negri@casasco.com.ar
Key Words	Stone formation; Kidney stone; matrix proteins; Uromodulin; Calgranulin; Proteomics
Core Tip	Several urinary proteins have been found in kidney stones matrix. In vitro and in vivo studies have shown that they have an important role in various process of calcium oxalate crystallization. Many of them have other functions in modulating oxidative stress, immune response and inflammation that could also influence stone formation. Yet, the exact role of these kidney stone matrix proteins  need to be established through more studies comparing urinary stone proteomics between stone formers and non-stone formers.
Publish Date	2023-03-21 06:38
Citation	Negri AL, Spivacow FR. Kidney stone matrix proteins: Their role in stone formation. World J Nephrol 2023; 12(2): 21-28
URL	https://www.wjgnet.com/2220-6124/full/v12/i2/21.htm
DOI	https://dx.doi.org/10.5527/wjn.v12.i2.21

Full Article (PDF)	WJN-12-21.pdf
Full Article (Word)	WJN-12-21.docx
Manuscript File	80913_Auto_Edited-YJM-Wang TQ-JLW.docx
Answering Reviewers	80913-Answering reviewers.pdf
Audio Core Tip	80913-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	80913-Conflict-of-interest statement.pdf
Copyright License Agreement	80913-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	80913-Language certificate.pdf
Peer-review Report	80913-Peer-review(s).pdf
Scientific Misconduct Check	80913-Bing-Ma YJ-2.jpg
Scientific Editor Work List	80913-Scientific editor work list.pdf
CrossCheck Report	80913-CrossCheck report.pdf