Publication Name	World Journal of Gastroenterology
Manuscript ID	8098
Country	China

Received	2013-12-15 17:34
Peer-Review Started	2013-12-16 11:16
To Make the First Decision	2014-01-15 13:14
Return for Revision	2014-01-20 19:01
Revised	2014-02-14 16:18
Second Decision	2014-06-13 15:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-06-13 16:16
Articles in Press	2014-06-13 16:26
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-06-21 19:50
Typeset the Manuscript	2014-10-16 17:47
Publish the Manuscript Online	2014-10-29 19:34

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Randomized Controlled Trial
Article Title	Therapeutic effects of globular adiponectin in diabetic rats with nonalcoholic fatty liver disease
Manuscript Source	Invited Manuscript
All Author List	Hong Ma, Fan Cui, Jing-Jing Dong, Guo-Ping You, Xiang-Jiu Yang, Hua-Dong Lu and Yan-Ling Huang
Funding Agency and Grant Number	Funding Agency Grant Number Science and Technology Project of Xiamen, China 3502Z20114016
Corresponding Author	Hong Ma, MD, PhD, Associate Professor, Department of Endocrinology, Zhongshan Hospital Xiamen University, 209 Hubin South Road, Xiamen 361004, Fujian Province, China. mah-169@163.com
Key Words	Adiponectin; Insulin secretion; Insulin receptor; Steatosis
Core Tip	Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease and is closely associated with obesity and type 2 diabetes mellitus (T2DM). Adiponectin is a fat-derived hormone with anti-diabetic properties, and evidence indicates that adiponectin plays a protective role in NAFLD. Our study focused on the beneficial roles of adiponectin in T2DM rats with NAFLD as a potential therapeutic target. The findings demonstrated that adiponectin exerts its beneficial effects in T2DM rats with NAFLD by promoting insulin secretion, mediating glucolipid metabolism, regulating insulin receptor expression and alleviating hepatic steatosis.
Publish Date	2014-10-29 19:34
Citation	Ma H, Cui F, Dong JJ, You GP, Yang XJ, Lu HD, Huang YL. Therapeutic effects of globular adiponectin in diabetic rats with nonalcoholic fatty liver disease. World J Gastroenterol 2014; 20(40): 14950-14957
URL	http://www.wjgnet.com/1007-9327/full/v20/i40/14950.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i40.14950

Full Article (PDF)	WJG-20-14950.pdf
Full Article (Word)	WJG-20-14950.doc
Manuscript File	8098-Review.doc
Answering Reviewers	8098-Answering reviewers.pdf
Copyright License Agreement	8098-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	8098-Language certificate.pdf
Peer-review Report	8098-Peer review(s).pdf
Scientific Misconduct Check	8098-CrossCheck.jpg
Scientific Editor Work List	8098-Scientific editor work list.pdf