4/23/2023 8:02:06 AM | Browse: 256 | Download: 727
| Publication Name | World Journal of Gastrointestinal Surgery |
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| Manuscript ID | 81207 |
| Country | China |
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| ISSN | 1948-9366 (online) |
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| Open Access | This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright | © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
| Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
| Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website | http://www.wjgnet.com |
| Category | Infectious Diseases | ||||||||
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| Manuscript Type | Basic Study | ||||||||
| Article Title | Acinous cell AR42J-derived exosome miR125b-5p promotes acute pancreatitis exacerbation by inhibiting M2 macrophage polarization via PI3K/AKT signaling pathway | ||||||||
| Manuscript Source | Unsolicited Manuscript | ||||||||
| All Author List | Zhi Zheng, Feng Cao, Yi-Xuan Ding, Jiong-Di Lu, Yuan-Qiao Fu, Lin Liu, Yu-Lin Guo, Shuang Liu, Hai-Chen Sun, Ye-Qing Cui and Fei Li | ||||||||
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| Corresponding Author | Fei Li, MD, PhD, Deputy Director, Professor, Surgeon, Department of General Surgery, Xuanwu Hospital, Capital Medical University, No. 45 Chang-chun Street, Xi-Cheng District , Beijing 100053, China. feili36@ccmu.edu.cn | ||||||||
| Key Words | Acute pancreatitis; Exosome; miR-125b-5p; Macrophage; Mechanism | ||||||||
| Core Tip | Our study confirmed that miR-125b-5p can promote the inflammatory response of acute pancreatitis (AP), and its potential targets were found via RNA sequencing assay. However, the likely mechanism remains unclear. Consequently, our study intends to elucidate the molecular mechanism of exosome-derived miR-125b-5p in promoting AP exacerbation from the perspective of the interaction between immune cells and acinar cells. | ||||||||
| Publish Date | 2023-04-23 08:02 | ||||||||
| Citation | Zheng Z, Cao F, Ding YX, Lu JD, Fu YQ, Liu L, Guo YL, Liu S, Sun HC, Cui YQ, Li F. Acinous cell AR42J-derived exosome miR125b-5p promotes acute pancreatitis exacerbation by inhibiting M2 macrophage polarization via PI3K/AKT signaling pathway. World J Gastrointest Surg 2023; 15(4): 600-620 | ||||||||
| URL | https://www.wjgnet.com/1948-9366/full/v15/i4/600.htm | ||||||||
| DOI | https://dx.doi.org/10.4240/wjgs.v15.i4.600 |
| Full Article (PDF) | WJGS-15-600.pdf |
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| Full Article (Word) | WJGS-15-600.docx |
| The ARRIVE Guidelines | 81207-The-ARRIVE-Guidelines-revision.pdf |
| Manuscript File | 81207_Auto_Edited-LM.docx |
| Answering Reviewers | 81207-Answering reviewers.pdf |
| Audio Core Tip | 81207-Audio core tip.m4a |
| Biostatistics Review Certificate | 81207-Biostatistics statement.pdf |
| Conflict-of-Interest Disclosure Form | 81207-Conflict-of-interest statement.pdf |
| Copyright License Agreement | 81207-Copyright license agreement.pdf |
| Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) | 81207-Grant application form(s).pdf |
| Institutional Animal Care and Use Committee Approval Form or Document | 81207-Institutional animal care and use committee statement.pdf |
| Institutional Review Board Approval Form or Document | 81207-Institutional review board statement.pdf |
| Non-Native Speakers of English Editing Certificate | 81207-Language certificate.pdf |
| Peer-review Report | 81207-Peer-review(s).pdf |
| Scientific Misconduct Check | 81207-Bing-Fan JR-2.png |
| Scientific Editor Work List | 81207-Scientific editor work list.pdf |
| CrossCheck Report | 81207-CrossCheck report.pdf |
| CrossCheck Report | 81207-CrossCheck.png |