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Articles Published Processes
1/12/2023 7:20:47 AM | Browse: 271 | Download: 687
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Received |
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2022-11-05 08:10 |
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Peer-Review Started |
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2022-11-05 08:12 |
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To Make the First Decision |
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Return for Revision |
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2022-11-22 08:49 |
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Revised |
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2022-12-03 04:15 |
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Second Decision |
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2022-12-23 03:15 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-12-23 09:00 |
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Articles in Press |
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2022-12-23 09:00 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-12-26 05:37 |
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Publish the Manuscript Online |
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2023-01-12 07:20 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Case Control Study |
| Article Title |
Microvesicles with mitochondrial content are increased in patients with sepsis and associated with inflammatory responses
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hai-Jun Zhang, Jin-Yi Li, Chao Wang and Guo-Qiang Zhong |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Guo-Qiang Zhong, PhD, Professor, Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning 530000, Guangxi Zhuang Autonomous Region, China. gq_zhong620@126.com |
| Key Words |
Sepsis; Microvesicles; Mitochondria; Microvesicles carrying mitochondrial content |
| Core Tip |
Sepsis is a systemic inflammatory response syndrome that can lead to multiple organ dysfunction related to endothelial injury. Increased numbers of circulating microvesicles carrying mitochondrial content (mitoMVs) have been found in patients with systemic lupus erythematosus, which feature inflammation as the pathogenic mechanism. Mitochondrial damage-associated molecular patterns have been shown to induce endothelial activation. Therefore, the presence and function of mitoMVs in sepsis was studied. We found that mitoMVs were increased in plasma of patients with sepsis, and were related to inflammatory markers and induced elevated expression of type-I-IFN-dependent genes in endothelial cells. |
| Publish Date |
2023-01-12 07:20 |
| Citation |
Zhang HJ, Li JY, Wang C, Zhong GQ. Microvesicles with mitochondrial content are increased in patients with sepsis and associated with inflammatory responses. World J Clin Cases 2023; 11(2): 342-356 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i2/342.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i2.342 |
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