Publication Name	World Journal of Gastroenterology
Manuscript ID	81367
Country	Japan

Received	2022-11-05 13:44
Peer-Review Started	2022-11-05 13:47
To Make the First Decision
Return for Revision	2022-11-17 01:51
Revised	2022-11-23 12:19
Second Decision	2023-02-01 03:23
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-02-01 21:37
Articles in Press	2023-02-01 21:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-02-03 00:44
Publish the Manuscript Online	2023-02-21 06:19

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Opinion Review
Article Title	Tranexamic acid may be a useful pharmacotherapy for endoscopically resistant small bowel angiodysplasia
Manuscript Source	Invited Manuscript
All Author List	Shunji Fujimori
ORCID	Author(s) ORCID Number Shunji Fujimori http://orcid.org/0000-0002-6214-2595
Funding Agency and Grant Number
Corresponding Author	Shunji Fujimori, AGAF, MD, PhD, Director, Director, Department of Gastroenterology, Chiba Hokusoh Hospital, Nippon Medical School, 1715, Kamagari, Inzai-City, Chiba 270-1694, Japan. s-fujimori@nms.ac.jp
Key Words	Angiodysplasia; Intestine; Hereditary hemorrhagic telangiectasia; Tranexamic acid; Endoscopic treatment; Pharmacotherapy
Core Tip	It is difficult to treat all multiple small bowel angiodysplasias (SBAD) endoscopically. Four main types of drugs, including somatostatin analogs, hormone therapy, thalidomide, and vascular endothelial growth factor-neutralizing antibodies, have been reported for use in gastrointestinal angiodysplasias (GIAD). However, there is no recommended pharmacotherapy for SBAD. Tranexamic acid is recommended for patients with GIAD in hereditary hemorrhagic telangiectasia who are difficult to treat endoscopically. Investigation of the use of tranexamic acid for SBAD is desired.
Publish Date	2023-02-21 06:19
Citation	Fujimori S. Tranexamic acid may be a useful pharmacotherapy for endoscopically resistant small bowel angiodysplasia. World J Gastroenterol 2023; 29(7): 1131-1138
URL	https://www.wjgnet.com/1007-9327/full/v29/i7/1131.htm
DOI	https://dx.doi.org/10.3748/wjg.v29.i7.1131

Full Article (PDF)	WJG-29-1131.pdf
Full Article (Word)	WJG-29-1131.docx
Manuscript File	81367_Auto_Edited-LM.docx
Answering Reviewers	81367-Answering reviewers.pdf
Audio Core Tip	81367-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	81367-Conflict-of-interest statement.pdf
Copyright License Agreement	81367-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	81367-Language certificate.pdf
Peer-review Report	81367-Peer-review(s).pdf
Scientific Misconduct Check	81367-Bing-Wang JJ-2.png
Scientific Editor Work List	81367-Scientific editor work list.pdf
CrossCheck Report	81367-CrossCheck report.pdf