Publication Name	World Journal of Clinical Oncology
Manuscript ID	81405
Country	Russia

Received	2022-11-17 09:17
Peer-Review Started	2022-11-17 09:19
To Make the First Decision
Return for Revision	2022-11-30 08:41
Revised	2022-12-09 09:57
Second Decision	2023-02-14 03:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-02-15 08:01
Articles in Press	2023-02-15 08:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-02-16 14:33
Publish the Manuscript Online	2023-02-21 03:35

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Review
Article Title	Hereditary cancer syndromes
Manuscript Source	Invited Manuscript
All Author List	Evgeny N Imyanitov, Ekaterina S Kuligina, Anna P Sokolenko, Evgeny N Suspitsin, Grigoriy A Yanus, Aglaya G Iyevleva, Alexandr O Ivantsov and Svetlana N Aleksakhina
ORCID	Author(s) ORCID Number Evgeny N Imyanitov http://orcid.org/0000-0003-4529-7891 Ekaterina S Kuligina http://orcid.org/0000-0002-2396-6540 Anna P Sokolenko http://orcid.org/0000-0001-6304-1609 Grigoriy A Yanus http://orcid.org/0000-0002-9844-4536 Svetlana N Aleksakhina http://orcid.org/0000-0002-2149-7728
Funding Agency and Grant Number	Funding Agency Grant Number The Russian Science Foundation 17-75-30027
Corresponding Author	Evgeny N Imyanitov, DSc, Professor, Department of Tumor Growth Biology, N.N. Petrov Institute of Oncology, Pesochny, Leningradskaya Str. 68, St.-Petersburg 197758, Russia. evgeny@imyanitov.spb.ru
Key Words	Hereditary cancer syndromes; Germline pathogenic variants; Cancer predisposition; Cancer treatment; Next-generation sequencing
Core Tip	There are many reviews describing particular types of hereditary cancer syndromes (HCSs) (e.g., hereditary breast-ovarian cancer, Lynch syndrome, Li-Fraumeni syndrome, etc.). However, for the last 15-20 years there were no publications providing a general overview on familial cancers. Our paper describes mechanisms underlying genetic cancer predisposition, lists major types of HCSs, and comments on therapeutic advances in the management of hereditary tumors.
Publish Date	2023-02-21 03:35
Citation	Imyanitov EN, Kuligina ES, Sokolenko AP, Suspitsin EN, Yanus GA, Iyevleva AG, Ivantsov AO, Aleksakhina SN. Hereditary cancer syndromes. World J Clin Oncol 2023; 14(2): 40-68
URL	https://www.wjgnet.com/2218-4333/full/v14/i2/40.htm
DOI	https://dx.doi.org/10.5306/wjco.v14.i2.40

Full Article (PDF)	WJCO-14-40.pdf
Full Article (Word)	WJCO-14-40.docx
Manuscript File	81405_Auto_Edited-JLW.docx
Answering Reviewers	81405-Answering reviewers.pdf
Audio Core Tip	81405-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	81405-Conflict-of-interest statement.pdf
Copyright License Agreement	81405-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	81405-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	81405-Language certificate.pdf
Peer-review Report	81405-Peer-review(s).pdf
Scientific Misconduct Check	81405-Bing-Fan JR-2.png
Scientific Editor Work List	81405-Scientific editor work list.pdf