Publication Name	World Journal of Clinical Oncology
Manuscript ID	8143
Country	France

Received	2013-12-18 10:30
Peer-Review Started	2013-12-18 15:43
To Make the First Decision	2014-03-12 17:10
Return for Revision	2014-03-22 16:31
Revised	2014-03-31 18:45
Second Decision	2014-05-14 16:26
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-14 16:37
Articles in Press	2014-05-23 09:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-18 10:09
Publish the Manuscript Online	2014-08-01 15:17

ISSN	2218-4333 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Biochemistry & Molecular Biology
Manuscript Type	Topic Highlights
Article Title	Regulation of the mRNA half-life in breast cancer
Manuscript Source	Invited Manuscript
All Author List	Paola Griseri and Gilles Pagès
Funding Agency and Grant Number	Funding Agency Grant Number Fondazione Umberto Veronesi to Griseri P French National Institute of Cancer (INCA) French Association for Cancer Research (ARC) Fondation de France, the Conseil Général des Alpes Maritimes Roche France and The “Association pour la Recherche sur les Tumeurs du Rein (ARTuR)”
Corresponding Author	Dr. Gilles Pagès, University of Nice-Sophia Antipolis, Institute for Research on Cancer and Aging of Nice (IRCAN) UMR CNRS/7284 U INSERM 1081, 33, av. Valombrose, 06189 Nice, France. gpages@unice.fr
Key Words	mRNA stability; Breast cancer; RNA binding proteins; MicroRNA; Alternative polyadenylation
Core Tip	This review article is dedicated to the understanding of the mechanisms involved in the regulation of mRNA half-life. mRNA relative stability is an important way to rapidly increase or decrease the level of a given gene. This process is a much more rapid mechanism compare to transcriptional regulation. Since many genes implicated in cancerous processes are regulated at the level of their half-life, the proteins and/or small non coding RNA implicated in this regulation may serve as relevant prognosis markers or predictive markers of the efficacy of chemotherapeutic agents.
Publish Date	2014-08-01 15:17
Citation	Griseri P, Pagès G. Regulation of the mRNA half-life in breast cancer. World J Clin Oncol 2014; 5(3): 323-334
URL	http://www.wjgnet.com/2218-4333/full/v5/i3/323.htm
DOI	http://dx.doi.org/10.5306/wjco.v5.i3.323

Full Article (PDF)	WJCO-5-323.pdf
Full Article (Word)	WJCO-5-323.doc
Manuscript File	8143-Review.docx
Answering Reviewers	8143-Answering reviewers.pdf
Copyright License Agreement	8143-Copyright assignment.pdf
Peer-review Report	8143-Peer review(s).pdf
Scientific Editor Work List	8143-Scientific editor work list.pdf