BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
2/24/2023 9:09:48 AM | Browse: 334 | Download: 954
 |
Received |
|
2022-11-10 13:34 |
|
Peer-Review Started |
|
2022-11-10 13:36 |
|
First Decision by Editorial Office Director |
|
2022-12-13 09:56 |
|
Return for Revision |
|
2022-12-13 09:56 |
|
Revised |
|
2022-12-26 13:56 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2023-02-07 03:31 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2023-02-07 07:05 |
|
Articles in Press |
|
2023-02-07 07:05 |
|
Edit the Manuscript by Language Editor |
|
2023-01-13 02:41 |
|
Typeset the Manuscript |
|
2023-02-08 08:39 |
|
Publish the Manuscript Online |
|
2023-02-24 09:09 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Dermatology |
| Manuscript Type |
Case Report |
| Article Title |
Hidrotic ectodermal dysplasia in a Chinese pedigree: A case report
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ming-Yi Liao, Hui Peng, Long-Nian Li, Tao Yang, Shi-Yin Xiong and Xiao-Ying Ye |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Xiao-Ying Ye, Doctor, Chief Physician, Professor, Department of Dermatology, First Affiliated Hospital of Gannan Medical University, No. 23 Qingnian Road, Zhanggong District, Ganzhou 341000, Jiangxi Province, China. 13870768166@139.com |
| Key Words |
Hidrotic ectodermal dysplasia; GJB6; Connexin; Gene sequencing; Cell transfection; Case report |
| Core Tip |
We report on a Chinese family with hidrotic ectodermal dysplasia (HED), with patients in the family presenting varying degrees of hair dysplasia, nail dysplasia, and palmoplantar hyperkeratosis. In addition, we performed a literature review of other reported HED genotypes and their corresponding phenotypes, which lays a foundation for subsequent studies on these associations. Overexpression vectors of the GJB6 gene and its variants (variation sites: c.31G>A, c.263C>T, c.110T>A) were established and transfected into a HaCaT cell model. The expression changes of related mRNA and proteins before and after gene editing were obtained by real-time reverse transcriptase-polymerase chain reaction and Western blot, respectively, to provide clues for subsequent pathogenesis studies. |
| Publish Date |
2023-02-24 09:09 |
| Citation |
Liao MY, Peng H, Li LN, Yang T, Xiong SY, Ye XY. Hidrotic ectodermal dysplasia in a Chinese pedigree: A case report. World J Clin Cases 2023; 11(6): 1403-1409 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i6/1403.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i6.1403 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
