Publication Name	World Journal of Clinical Oncology
Manuscript ID	8151
Country	Brazil

Received	2013-12-18 13:48
Peer-Review Started	2013-12-18 16:27
To Make the First Decision	2014-01-23 17:20
Return for Revision	2014-02-20 22:20
Revised	2014-02-22 00:16
Second Decision	2014-03-17 14:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-17 14:45
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-07 14:41
Publish the Manuscript Online	2014-05-12 18:06

ISSN	2218-4333 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Topic Highlights
Article Title	Relationship between head and neck cancer therapy and some genetic endpoints
Manuscript Source	Invited Manuscript
All Author List	Eliana Maria Minicucci, Glenda Nicioli da Silva and Daisy Maria Fávero Salvadori
Funding Agency and Grant Number
Corresponding Author	Daisy Maria Fávero Salvadori, PhD, Departamento de Patologia, Faculdade de Medicina de Botucatu, Univ. Estadual Paulista, UNESP, Botucatu Distrito de Rubião Júnior, s/nº, Botucatu, SP 18618-000, Brazil. dfavero@fmb.unesp.br
Key Words	Chemotherapy; Head and neck cancer; Radiotherapy; Toxicogenetic; Toxicogenomic
Core Tip	The main therapies for head and neck cancer (HNC) are surgery, radiotherapy (RT) and chemotherapy. Considering that both RT and chemotherapeutical drugs can interact with the DNA, one of the important, late-occurring complications is a therapy-related secondary tumor resulting from the genotoxic effects of the therapy on the healthy cells. This review presents an update of the toxicogenetic and toxicogenomic effects of HNC treatments, highlighting the main mechanisms evolved in the secondary damage caused by RT and chemotherapies.
Publish Date	2014-05-12 18:06
Citation	Minicucci EM, da Silva GN, Salvadori DMF. Relationship between head and neck cancer therapy and some genetic endpoints. World J Clin Oncol 2014; 5(2): 93-102
URL	http://www.wjgnet.com/2218-4333/full/v5/i2/93.htm
DOI	http://dx.doi.org/10.5306/wjco.v5.i2.93

Full Article (PDF)	WJCO-5-93.pdf
Full Article (Word)	WJCO-5-93.doc
Manuscript File	8151-Review.doc
Answering Reviewers	8151-Answering reviewers.pdf
Copyright License Agreement	8151-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	8151-Language certificate.doc
Peer-review Report	8151-Peer reviewer(s).pdf
Scientific Editor Work List	8151-Scientific editor work list.doc