Publication Name	World Journal of Clinical Oncology
Manuscript ID	8163
Country	United States

Received	2013-12-18 16:08
Peer-Review Started	2013-12-18 16:38
To Make the First Decision	2014-02-27 11:25
Return for Revision	2014-03-05 09:58
Revised	2014-03-27 10:35
Second Decision	2014-04-16 16:03
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-16 16:10
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-07 14:45
Publish the Manuscript Online	2014-05-12 18:06

ISSN	2218-4333 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Minireviews
Article Title	Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma
Manuscript Source	Unsolicited Manuscript
All Author List	Erik W Larson, Halloran E Peterson, Wayne T Lamoreaux, Alexander R MacKay, Robert K Fairbanks, Jason A Call, Jonathan D Carlson, Benjamin C Ling, John J Demakas, Barton S Cooke and Christopher M Lee
Funding Agency and Grant Number
Corresponding Author	Christopher M. Lee, MD Radiation Oncology University of Washington - School of Medicine Gamma Knife of Spokane and Cancer Care Northwest 910 W 5th Ave, Suite 102, Spokane, WA 99204 USA Phone: (509) 228-1000 Fax: (509) 228-1183 Email: lee@ccnw.net
Key Words	Gamma Knife radiosurgery; Malignant glioma; Glioblastoma; Salvage therapy; Stereotactic radiosurgery; Multimodal treatment
Core Tip	Glioblastoma is the most common malignant primary neoplasm of the brain. Despite aggressive, upfront therapy, most patients will experience a recurrence of their tumor six months after treatment. This review article analyzes the outcomes of clinical trials that utilized Gamma Knife radiosurgery as salvage therapy for recurrent glioblastoma. Other modalities of radiosurgery were excluded from this study as there is variability in the targeting precision and radiation dosage fall off. Gamma Knife can be used to target tumors that are adjacent to eloquent brain tissue, thus allowing it to treat a wider population of patients, improving overall survival.
Publish Date	2014-05-12 18:06
Citation	Larson EW, Peterson HE, Lamoreaux WT, MacKay AR, Fairbanks RK, Call JA, Carlson JD, Ling BC, Demakas JJ, Cooke BS, Lee CM. Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma. World J Clin Oncol 2014; 5(2): 142-148
URL	http://www.wjgnet.com/2218-4333/full/v5/i2/142.htm
DOI	http://dx.doi.org/10.5306/wjco.v5.i2.142

Full Article (PDF)	WJCO-5-142.pdf
Full Article (Word)	WJCO-5-142.doc
Manuscript File	8163-Review.docx
Answering Reviewers	8163-Answering reviewers.pdf
Copyright License Agreement	8163-Copyright assignment.pdf
Peer-review Report	8163-Peer review(s).pdf
Scientific Editor Work List	8163-Scientific editor work list.doc