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2/15/2023 12:44:08 AM | Browse: 116 | Download: 339
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 81632
Country China
Received
2022-11-18 02:19
Peer-Review Started
2022-11-18 02:21
To Make the First Decision
Return for Revision
2023-01-03 07:14
Revised
2023-01-11 13:19
Second Decision
2023-02-02 03:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-02-02 13:14
Articles in Press
2023-02-02 13:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-02-07 06:44
Publish the Manuscript Online
2023-02-15 00:44
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Evaluation of polygenic risk score for risk prediction of gastric cancer
Manuscript Source Invited Manuscript
All Author List Xiao-Yu Wang, Li-Li Wang, Lin Xu, Shu-Zhen Liang, Meng-Chao Yu, Qiu-Yue Zhang and Quan-Jiang Dong
ORCID
Author(s) ORCID Number
Xiao-Yu Wang http://orcid.org/0000-0002-3278-0879
Li-Li Wang http://orcid.org/0000-0002-3607-0786
Lin Xu http://orcid.org/0000-0003-3098-8251
Quan-Jiang Dong http://orcid.org/0000-0002-5226-7853
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 31870777
Corresponding Author Quan-Jiang Dong, MD, PhD, Chief Doctor, Professor, Central Laboratories and Department of Gastroenterology, Qingdao Municipal Hospital, Qingdao University, No. 5 Donghai Middle Road, Qingdao 266071, Shandong Province, China. allyking114@126.com
Key Words Polygenic risk scores; Gastric cancer; Helicobacter pylori; Gastric microbiome
Core Tip A systematic review was conducted to evaluate current polygenic risk score (PRS) models in gastric cancer risk prediction. Our study showed that PRS models had the potential to predict the risk of gastric cancer with a moderate accuracy. The prediction models’ performance could be improved after incorporating epidemiological factors or Helicobacter pylori (H. pylori) status. The potential of H. pylori genomic variations and members of the gastric microbiome were discussed as candidates for gastric cancer prediction models.
Publish Date 2023-02-15 00:44
Citation Wang XY, Wang LL, Xu L, Liang SZ, Yu MC, Zhang QY, Dong QJ. Evaluation of polygenic risk score for risk prediction of gastric cancer. World J Gastrointest Oncol 2023; 15(2): 276-285
URL https://www.wjgnet.com/1948-5204/full/v15/i2/276.htm
DOI https://dx.doi.org/10.4251/wjgo.v15.i2.276
Full Article (PDF) WJGO-15-276.pdf
Full Article (Word) WJGO-15-276.docx
Manuscript File 81632_Auto_Edited-LM.docx
Answering Reviewers 81632-Answering reviewers.pdf
Audio Core Tip 81632-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 81632-Conflict-of-interest statement.pdf
Copyright License Agreement 81632-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 81632-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 81632-Language certificate.pdf
Supplementary Material 81632-Supplementary material.pdf
Peer-review Report 81632-Peer-review(s).pdf
Scientific Misconduct Check 81632-Bing-Chen YL-2.png
Scientific Editor Work List 81632-Scientific editor work list.pdf