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Articles Published Processes
5/16/2023 7:16:46 AM | Browse: 189 | Download: 572
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Received |
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2022-11-28 13:34 |
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Peer-Review Started |
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2022-11-28 13:36 |
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To Make the First Decision |
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Return for Revision |
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2023-02-15 07:21 |
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Revised |
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2023-03-06 02:05 |
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Second Decision |
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2023-04-11 03:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-04-11 17:35 |
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Articles in Press |
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2023-04-11 17:35 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-04-16 19:39 |
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Typeset the Manuscript |
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2023-05-08 06:23 |
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Publish the Manuscript Online |
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2023-05-16 07:16 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Basic Study |
Article Title |
TATA-box-binding protein-associated factor 15 is a novel biomarker that promotes cell proliferation and migration in gastrointestinal stromal tumor
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Cheng-Ming Guo, Li Tang, Xu Li and Liu-Ye Huang |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
81870453 |
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Corresponding Author |
Liu-Ye Huang, N/A, Academic Research, Chief Doctor, Chief Physician, Professor, Research Scientist, Department of Gastroenterology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, No. 20 Yuhuangding East Road, Yantai 264000, Shandong Province, China. liuye_huang@163.com |
Key Words |
Gastrointestinal stromal tumor; Proteomics; TATA-box-binding protein-associated factor 15; Biomarker; Cell proliferation; Cell migration |
Core Tip |
TATA-box-binding protein-associated factor 15 (TAF15) was upregulated in Gastrointestinal stromal tumor (GIST) cells and tissues, and was associated with a poor prognosis of GIST patients. TAF15 promotes cell proliferation and migration of GIST in vitro and tumour growth in vivo via the activation of RAF1/MEK/ERK signaling pathway. Therefore, TAF15 is expected to be a novel potential molecular biomarker or therapeutic target of GIST. |
Publish Date |
2023-05-16 07:16 |
Citation |
Guo CM, Tang L, Li X, Huang LY. TATA-box-binding protein-associated factor 15 is a novel biomarker that promotes cell proliferation and migration in gastrointestinal stromal tumor. World J Gastroenterol 2023; 29(19): 2932-2949 |
URL |
https://www.wjgnet.com/1007-9327/full/v29/i19/2932.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v29.i19.2932 |
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