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Articles Published Processes
7/12/2023 11:13:16 AM | Browse: 205 | Download: 657
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Received |
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2022-12-07 09:41 |
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Peer-Review Started |
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2022-12-07 09:43 |
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To Make the First Decision |
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Return for Revision |
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2023-01-18 15:35 |
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Revised |
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2023-03-30 14:20 |
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Second Decision |
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2023-04-28 03:33 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-05-01 05:55 |
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Articles in Press |
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2023-05-01 05:55 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-07-03 10:58 |
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Publish the Manuscript Online |
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2023-07-12 11:13 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
ENTPD1-AS1–miR-144-3p-mediated high expression of COL5A2 correlates with poor prognosis and macrophage infiltration in gastric cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Han-Mei Yuan, Xiao-Feng Pu, Hui Wu and Chao Wu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81971489 |
| Natural Science Foundation of Guangdong Province |
2022A1515011122 |
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| Corresponding Author |
Chao Wu, PhD, Professor, Department of Laboratory Medicine, The Eighth Affiliated Hospital, Sun Yat-sen University, No. 3025 Shennan Zhong Lu, Shenzhen 518033, Guangdong Province, China. chaowu261@163.com |
| Key Words |
COL5A2; Noncoding RNAs; Macrophage infiltration; Prognosis; Gastric cancer |
| Core Tip |
Gastric cancer (GC) is a malignant tumor with high fatality rate. Competing endogenous RNA network and infiltration of immune cells play an important role in the development of GC. In this study, we verified that high expression of COL5A2 was closely related to poor prognosis and was an independent risk factor for GC. We predicted and validated that long noncoding RNA ENTPD1-AS1 regulated the expression of COL5A2 through sponging miR-144-3p. Additionally, we confirmed that upregulation of COL5A2 expression strongly correlated with immune infiltration of macrophages. ENTPD1-AS1-miR-144-3p-COL5A2 might be a new therapeutic target for GC. |
| Publish Date |
2023-07-12 11:13 |
| Citation |
Yuan HM, Pu XF, Wu H, Wu C. ENTPD1-AS1–miR-144-3p-mediated high expression of COL5A2 correlates with poor prognosis and macrophage infiltration in gastric cancer. World J Gastrointest Oncol 2023; 15(7): 1182-1199 |
| URL |
https://www.wjgnet.com/1948-5204/full/v15/i7/1182.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v15.i7.1182 |
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