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5/16/2023 9:24:22 AM | Browse: 83 | Download: 208
Publication Name World Journal of Clinical Cases
Manuscript ID 82037
Country China
Received
2022-12-04 14:05
Peer-Review Started
2022-12-04 14:07
To Make the First Decision
Return for Revision
2023-02-07 09:04
Revised
2023-02-17 18:08
Second Decision
2023-04-06 03:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-04-06 07:57
Articles in Press
2023-04-06 07:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-04-25 07:43
Publish the Manuscript Online
2023-05-16 09:24
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, General & Internal
Manuscript Type Case Report
Article Title Immune checkpoint inhibitor therapy-induced autoimmune polyendocrine syndrome type II and Crohn’s disease: A case report
Manuscript Source Unsolicited Manuscript
All Author List Mei-Juan Gao, Yan Xu and Wen-Bo Wang
ORCID
Author(s) ORCID Number
Mei-Juan Gao http://orcid.org/0000-0002-8324-9877
Funding Agency and Grant Number
Corresponding Author Mei-Juan Gao, MD, Chief Physician, Department of Endocrinology, Peking University Shougang Hospital, No. 9, Jinyuanzhuang Road, Beijing 100041, China. gmjluhe@163.com
Key Words Immune checkpoint inhibitor; Programmed cell death protein 1 ligand; Autoimmune polyendocrine syndrome type II; Type 1 diabetes mellitus; Thyroiditis; Crohn’s disease; Case report
Core Tip We report a rare case of multi-system damage induced by cancer therapy with protein 1 ligand inhibitor teriprizumab. A man with squamous cell carcinoma of oropharynx on a combination regimen of teriprizumab, docetaxel, and cisplatin developed autoimmune polyendocrine syndrome type II (APS-2) including thyroiditis and type 1 diabetes mellitus (T1DM) and Crohn’s disease (CD). This case report highlights the possibility of chronic immune toxicities and the long-term implications of cancer immunotherapy. To the best of our knowledge, this is the first reported case of concurrent atypical APS-2 (including T1DM and thyrotoxicosis) and CD in a patient receiving immunotherapy for metastatic nasopharyngeal carcinoma.
Publish Date 2023-05-16 09:24
Citation Gao MJ, Xu Y, Wang WB. Immune checkpoint inhibitor therapy-induced autoimmune polyendocrine syndrome type II and Crohn’s disease: A case report. World J Clin Cases 2023; 11(14): 3267-3274
URL https://www.wjgnet.com/2307-8960/full/v11/i14/3267.htm
DOI https://dx.doi.org/10.12998/wjcc.v11.i14.3267
Full Article (PDF) WJCC-11-3267.pdf
Full Article (Word) WJCC-11-3267.docx
CARE Checklist–2016 82037-CARE-Checklist–2016-revision.doc
Manuscript File 82037_Auto_Edited-JLW.docx
Answering Reviewers 82037-Answering reviewers.pdf
Audio Core Tip 82037-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 82037-Conflict-of-interest statement.pdf
Copyright License Agreement 82037-Copyright license agreement.pdf
Signed Consent for Treatment Form(s) or Document(s) 82037-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 82037-Language certificate.pdf
Supplementary Material 82037-Supplementary material.pdf
Peer-review Report 82037-Peer-review(s).pdf
Scientific Misconduct Check 82037-Bing-Li L-2.png
Scientific Editor Work List 82037-Scientific editor work list.pdf