Publication Name	World Journal of Gastroenterology
Manuscript ID	8210
Country	Finland

Received	2013-12-26 08:52
Peer-Review Started	2013-12-26 14:43
To Make the First Decision	2014-01-15 19:34
Return for Revision	2014-01-20 19:41
Revised
Second Decision	2014-05-19 11:06
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-19 11:13
Articles in Press	2014-05-23 09:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-21 09:22
Publish the Manuscript Online	2014-09-07 13:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Impacts of common factors of life style on serum liver enzymes
Manuscript Source	Invited Manuscript
All Author List	Joanna Danielsson, Päivikki Kangastupa, Tiina Laatikainen, Mauri Aalto and Onni Niemelä
Funding Agency and Grant Number	Funding Agency Grant Number Competitive State Research Financing of the Expert Responsibility area of Seinäjoki Central Hospital University of Tampere VTR110
Corresponding Author	Onni Niemelä, MD, Professor, Department of Laboratory Medicine, Seinäjoki Central Hospital and University of Tampere, Hanneksenrinne 7, 60220 Seinäjoki, Finland. onni.niemela@epshp.fi
Key Words	Alcohol; Obesity; Aging; Smoking; Liver enzymes; Oxidative stress
Core Tip	The present study among 6269 apparently healthy individuals shows that the early changes in serum alanine aminotransferase and gamma-glutamyltransferase levels show distinct age- and gender-dependent variation according to the amount of alcohol drinking and the presence or absence of overweight. Coffee consumption and smoking also modulate the enzyme levels with different sensitivities between genders. The data should be implicated in the assessment of health risks associated with such factors of life style and when revisiting the concept of normal limits in the clinical use of liver enzymes.
Publish Date	2014-09-07 13:31
Citation	Danielsson J, Kangastupa P, Laatikainen T, Aalto M, Niemelä O. Impacts of common factors of life style on serum liver enzymes. World J Gastroenterol 2014; 20(33): 11743-11752
URL	http://www.wjgnet.com/1007-9327/full/v20/i33/11743.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i33.11743

Full Article (PDF)	WJG-20-11743.pdf
Full Article (Word)	WJG-20-11743.doc
Manuscript File	8210-Review.doc
Answering Reviewers	8210-Answering reviewers.pdf
Copyright License Agreement	8210-Copyright assignment.pdf
Peer-review Report	8210-Peer review.pdf
Scientific Editor Work List	8210-Scientific editor work list.pdf