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3/2/2023 1:29:51 PM | Browse: 168 | Download: 470
Publication Name World Journal of Clinical Cases
Manuscript ID 82156
Country China
Received
2022-12-07 11:35
Peer-Review Started
2022-12-07 11:36
To Make the First Decision
Return for Revision
2023-01-03 01:40
Revised
2023-01-04 16:55
Second Decision
2023-02-14 03:31
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2023-02-15 07:48
Articles in Press
2023-02-15 07:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
2023-02-12 14:29
Typeset the Manuscript
2023-02-16 08:28
Publish the Manuscript Online
2023-03-02 13:29
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Neurosciences
Manuscript Type Clinical and Translational Research
Article Title Analysis of differentially expressed genes related to cerebral ischaemia in young rats based on the Gene Expression Omnibus database
Manuscript Source Unsolicited Manuscript
All Author List Yu Xia, Han Liu and Rui Zhu
ORCID
Author(s) ORCID Number
Yu Xia http://orcid.org/0000-0003-3734-4280
Rui Zhu http://orcid.org/0000-0001-8142-3440
Funding Agency and Grant Number
Corresponding Author Rui Zhu, MD, Chief Physician, Department of Neurology, The Third People’s Hospital of Hefei (The Third Clinical College of Anhui Medical University), No. 204 Wangjiang East Road, Hefei 230022, Anhui Province, China. masterzr117@sina.com
Key Words Gene Expression Omnibus database; Cerebral infarction in young people; Rats; Differential gene enrichment analysis; Pathway
Core Tip This study mainly used the analysis technology related to biogenetic informatics to retrieve the samples of young cerebral ischemia rats from the authoritative global Gene Expression Omnibus database, identified the differential genes related to the onset of cerebral ischemia in young rats through the differential gene analysis method, further carried out Gene Ontology function enrichment analysis and Kyoto Encyclopedia of Genes and Genomes function enrichment analysis, and finally obtained the key gene pathway that affects ischaemic stroke in young rats. The findings provide clues for further realizing the transformation of basic medicine into clinical practical application, so as to finally realize the precise target intervention of young people with ischemic stroke and reduce the disability rate and mortality rate.
Publish Date 2023-03-02 13:29
Citation Xia Y, Liu H, Zhu R. Analysis of differentially expressed genes related to cerebral ischaemia in young rats based on the Gene Expression Omnibus database. World J Clin Cases 2023; 11(7): 1467-1476
URL https://www.wjgnet.com/2307-8960/full/v11/i7/1467.htm
DOI https://dx.doi.org/10.12998/wjcc.v11.i7.1467
Full Article (PDF) WJCC-11-1467.pdf
Full Article (Word) WJCC-11-1467.docx
Manuscript File 82156_Auto_Edited-LLW-WangTQ-JLW.docx
Answering Reviewers 82156-Answering reviewers.pdf
Audio Core Tip 82156-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 82156-Conflict-of-interest statement.pdf
Copyright License Agreement 82156-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 82156-Language certificate.pdf
Peer-review Report 82156-Peer-review(s).pdf
Scientific Misconduct Check 82156-Bing-Wang LL-2.png
Scientific Editor Work List 82156-Scientific editor work list.pdf
CrossCheck Report 82156-CrossCheck report.pdf