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Articles Published Processes
3/7/2023 8:12:13 AM | Browse: 197 | Download: 601
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Received |
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2022-12-13 10:16 |
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Peer-Review Started |
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2022-12-13 10:19 |
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To Make the First Decision |
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Return for Revision |
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2023-01-19 08:54 |
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Revised |
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2023-01-20 11:18 |
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Second Decision |
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2023-02-21 03:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-02-21 07:26 |
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Articles in Press |
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2023-02-21 07:26 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-02-27 09:25 |
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Publish the Manuscript Online |
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2023-03-07 08:12 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Patients with hepatocellular carcinoma that die during the first year of liver transplantation have high blood sFasL concentrations
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Leonardo Lorente, Sergio T Rodriguez, Pablo Sanz, Agustín F González-Rivero, Antonia Pérez-Cejas, Javier Padilla, Dácil Díaz, Antonio González, María M Martín, Alejandro Jiménez, Purificación Cerro, Julián Portero and Manuel A Barrera |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Leonardo Lorente, MD, PhD, Attending Doctor, Medical Assistant, Intensive Care Unit, Hospital Universitario de Canarias, La Laguna 38320, Spain. lorentemartin@msn.com |
| Key Words |
sFasL; Hepatocellular carcinoma; Liver transplantation; Mortality; Outcome |
| Core Tip |
Fas ligand (FasL) is one of the main ligands that activate apoptosis via the extrinsic pathway. Elevated blood concentrations of soluble FasL (sFasL) have not been found in patients with acute liver transplant (LT) rejection; however, the sample sizes of those studies were small. We found in this retrospective study of 127 patients with hepatocellular carcinoma underwent to LT that patients that die during the first year of LT have higher blood sFasL concentrations previously to LT than those who that remain alive. The beneficial results of blockade of the Fas system in animal models could motivate its investigation in these patients. |
| Publish Date |
2023-03-07 08:12 |
| Citation |
Lorente L, Rodriguez ST, Sanz P, González-Rivero AF, Pérez-Cejas A, Padilla J, Díaz D, González A, Martín MM, Jiménez A, Cerro P, Portero J, Barrera MA. Patients with hepatocellular carcinoma that die during the first year of liver transplantation have high blood sFasL concentrations prior to transplantation. World J Clin Cases 2023; 11(8): 1753-1760 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i8/1753.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i8.1753 |
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