Publication Name	World Journal of Stem Cells
Manuscript ID	82312
Country	Taiwan

Received	2022-12-15 00:54
Peer-Review Started	2022-12-15 00:57
To Make the First Decision
Return for Revision	2023-01-18 22:15
Revised	2023-01-19 12:15
Second Decision	2023-03-15 03:08
Accepted by Journal Editor-in-Chief	2023-03-16 00:46
Accepted by Company Editor-in-Chief	2023-03-21 19:09
Articles in Press	2023-03-21 19:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-04-18 04:19
Publish the Manuscript Online	2023-04-26 08:16

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Transplantation
Manuscript Type	Minireviews
Article Title	Harnessing and honing mesenchymal stem/stromal cells for the amelioration of graft-versus-host disease
Manuscript Source	Invited Manuscript
All Author List	Tang-Her Jaing, Tsung-Yen Chang and Chia-Chi Chiu
ORCID	Author(s) ORCID Number Tang-Her Jaing http://orcid.org/0000-0002-5407-1555 Tsung-Yen Chang http://orcid.org/0000-0003-1123-4235
Funding Agency and Grant Number
Corresponding Author	Tang-Her Jaing, MD, Chief Physician, Director, Professor, Division of Hematology, Oncology, Department of Pediatrics, Chang Gung Children’s Hospital, Chang Gung University, No. 5 Fu-Shin Street, Kwei-Shan, Taoyuan 333, Taiwan. jaing001@cgmh.org.tw
Key Words	Mesenchymal stem/stromal cells; Graft-versus-host disease; Immunomodulatory; Adaptive immunity; Exosomes
Core Tip	This article provides insights into the use of validated mesenchymal stem/stromal cells (MSCs) as a potential treatment strategy for graft-versus-host disease (GVHD) in hematopoietic stem cell transplantation (HSCT). Current prevention and treatment options involve immunosuppression, which can hinder immune recovery and limit the graft-versus-tumor effect. By using MSCs, clinicians can effectively treat GVHD, identify high-risk patients, and stratify patients based on disease severity. Therefore, MSCs can aid in promoting engraftment, ameliorating acute GVHD, and preventing chronic GVHD, making them an attractive option for HSCT.
Publish Date	2023-04-26 08:16
Citation	Jaing TH, Chang TY, Chiu CC. Harnessing and honing mesenchymal stem/stromal cells for the amelioration of graft-versus-host disease. World J Stem Cells 2023; 15(4): 221-234
URL	https://www.wjgnet.com/1948-0210/full/v15/i4/221.htm
DOI	https://dx.doi.org/10.4252/wjsc.v15.i4.221

Full Article (PDF)	WJSC-15-221.pdf
Full Article (Word)	WJSC-15-221.docx
Manuscript File	82312_Auto_Edited-LM.docx
Answering Reviewers	82312-Answering reviewers.pdf
Audio Core Tip	82312-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	82312-Conflict-of-interest statement.pdf
Copyright License Agreement	82312-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	82312-Language certificate.pdf
Peer-review Report	82312-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	82312-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	82312-Bing-Yan JP-2.png
Scientific Editor Work List	82312-Scientific editor work list.pdf