| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Case Report |
| Article Title |
Metastatic gastric cancer from breast carcinoma presenting with paraneoplastic rheumatic syndrome: A case report
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Marília Bortoluz Rech, Eduarda Renz da-Cruz, Karina Salgado, Raul Angelo Balbinot, Silvana Sartori Balbinot and Jonathan Soldera |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Jonathan Soldera, MD, MSc, Associate Professor, Staff Physician, Department of Clinical Gastroenterology, Universidade de Caxias do Sul, Rua Francisco Getúlio Vargas, 1130, Caxias do Sul 95070-560, Rio Grande do Sul, Brazil. jonathansoldera@gmail.com |
| Key Words |
Breast cancer; Gastric metastasis; Anemia; Paraneoplastic syndrome; Case report |
| Core Tip |
Breast cancer, the most frequently diagnosed type of cancer worldwide, is the leading cause of death due to malignant disease in women. We present the case of a female patient, 73 years of age, who sought care due to weakness, mild abdominal pain, arthralgia, and weight loss. She was taking anastrazole as a maintenance therapy for a localized breast cancer. She presented with moderate anemia and elevated acute phase markers. Upper digestive endoscopy showed isolated erosion in the gastric corpus. In anatomopathological study, the lesion was found to be compatible with signet-ring cell adenocarcinoma, while in in immunohistochemistry it was confirmed to be a metastasis of breast carcinoma, being positive for estrogen antibody. Further imaging studies determined numerous proximal bone metastases. The patient has been treated and followed up for 6 mo, and her anemia, arthralgias and acute phase markers have normalized. Systemic treatment strategies appear to be the best choice for gastric metastasis from breast cancer, providing disease control and relapse-free survival. Prospective studies with longer follow up are needed to better understand the biological, pathological, and clinicopathological characteristics and outcomes of the endoscopic features associated with metastatic gastric cancer from breast carcinoma. |
| Publish Date |
2023-05-16 09:24 |
| Citation |
Rech MB, Cruz ER, Salgado K, Balbinot RA, Balbinot SS, Soldera J. Metastatic gastric cancer from breast carcinoma presenting with paraneoplastic rheumatic syndrome: A case report. World J Clin Cases 2023; 11(14): 3282-3287 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i14/3282.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i14.3282 |
