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5/7/2023 7:47:34 AM | Browse: 115 | Download: 295
Publication Name World Journal of Gastroenterology
Manuscript ID 82564
Country Finland
Received
2022-12-27 20:49
Peer-Review Started
2022-12-27 20:50
To Make the First Decision
Return for Revision
2023-01-22 06:15
Revised
2023-02-06 07:03
Second Decision
2023-04-11 03:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-04-11 17:00
Articles in Press
2023-04-11 17:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
2023-03-31 22:43
Typeset the Manuscript
2023-04-23 00:26
Publish the Manuscript Online
2023-05-07 07:47
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Randomized Controlled Trial
Article Title Fecal microbiota transplantation for the maintenance of remission in patients with ulcerative colitis: A randomized controlled trial
Manuscript Source Unsolicited Manuscript
All Author List Perttu Lahtinen, Jonna Jalanka, Eero Mattila, Jyrki Tillonen, Paula Bergman, Reetta Satokari and Perttu Arkkila
ORCID
Author(s) ORCID Number
Perttu Lahtinen http://orcid.org/0000-0001-6430-4642
Jonna Jalanka http://orcid.org/0000-0002-3847-8136
Eero Mattila http://orcid.org/0000-0001-9787-7674
Jyrki Tillonen http://orcid.org/0000-0002-5661-9385
Paula Bergman http://orcid.org/0000-0003-4672-2554
Reetta Satokari http://orcid.org/0000-0002-4258-3414
Perttu Arkkila http://orcid.org/0000-0003-2194-0424
Funding Agency and Grant Number
Funding Agency Grant Number
Sigrid Juselius Foundation and University of Helsinki (A Three-year Grant)
Academy of Finland (Reetta Satokari) 323156
The Competitive State Research Financing (Perttu Lahtinen) 200230042
The Ella and Georg Ehrnrooth Foundation (Perttu Arkkila)
Corresponding Author Perttu Lahtinen, MD, Chief Doctor, Department of Gastroenterology, Päijät-Häme Central Hospital, Keskussairaalankatu 7, Lahti 15610, Finland. perttu.lahtinen@phhyky.fi
Key Words Fecal microbial transplantation; Ulcerative colitis; Quality of life; Maintenance of remission; Inflammatory bowel disease; Fecal calprotectin
Core Tip This randomized controlled trial compared the efficacy of Fecal microbial transplantation (FMT) via colonoscopy and autologous placebo containing patients’ own feces for the maintenance of remission in 48 patients with ulcerative colitis. The colitis activity was measured with the clinical Mayo score and fecal calprotectin. There was no significant difference in relapses between the groups at the one-year follow-up. Remission remained in 54% of the patients in the FMT group compared to 41% in the placebo group. There was no difference in the adverse events between the groups.
Publish Date 2023-05-07 07:47
Citation Lahtinen P, Jalanka J, Mattila E, Tillonen J, Bergman P, Satokari R, Arkkila P. Fecal microbiota transplantation for the maintenance of remission in patients with ulcerative colitis: A randomized controlled trial. World J Gastroenterol 2023; 29(17): 2666-2678
URL https://www.wjgnet.com/1007-9327/full/v29/i17/2666.htm
DOI https://dx.doi.org/10.3748/wjg.v29.i17.2666
Full Article (PDF) WJG-29-2666.pdf
Full Article (Word) WJG-29-2666.docx
CONSORT 2010 Statement 82564-CONSORT-2010-Statement-revision.pdf
Manuscript File 82564_Auto_Edited-LM.docx
Answering Reviewers 82564-Answering reviewers.pdf
Audio Core Tip 82564-Audio core tip.m4a
Biostatistics Review Certificate 82564-Biostatistics statement.pdf
Clinical Trial Registration Statement 82564-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form 82564-Conflict-of-interest statement.pdf
Copyright License Agreement 82564-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 82564-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 82564-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 82564-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 82564-Language certificate.pdf
Supplementary Material 82564-Supplementary material.pdf
Peer-review Report 82564-Peer-review(s).pdf
Scientific Misconduct Check 82564-Bing-Fan JR-2.png
Scientific Editor Work List 82564-Scientific editor work list.pdf