Publication Name	World Journal of Stem Cells
Manuscript ID	82568
Country	India

Received	2022-12-22 14:55
Peer-Review Started	2022-12-22 14:57
To Make the First Decision
Return for Revision	2023-01-31 00:24
Revised	2023-02-21 09:40
Second Decision	2023-04-07 02:31
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-04-07 08:00
Articles in Press	2023-04-07 08:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-04-24 06:31
Publish the Manuscript Online	2023-05-26 11:17

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cell Biology
Manuscript Type	Minireviews
Article Title	Molecular signaling in cancer stem cells of tongue squamous cell carcinoma: Therapeutic implications and challenges
Manuscript Source	Invited Manuscript
All Author List	Priyanka Joshi and Sanjeev Waghmare
ORCID	Author(s) ORCID Number Sanjeev Waghmare http://orcid.org/0000-0002-3693-5620
Funding Agency and Grant Number
Corresponding Author	Sanjeev Waghmare, PhD, Senior Scientist, Stem Cell Biology, Cancer Research Institute, Advanced Centre for Treatment Research and Education in Cancer, Tata Memorial Centre, Sector 22, Utsav Chowk-CISF Road, Kharghar, Navi Mumbai 410210, India. swaghmare@actrec.gov.in
Key Words	Head and neck squamous cell carcinoma; Cancer stem cells; Signaling; Tongue squamous cell carcinoma
Core Tip	Tongue squamous cell carcinoma is one of the most common and aggressive oral cavity carcinomas, particularly among the Indian population. Despite of various treatment strategies employed, the survival rates of the patients remain poor. A rare population i.e., cancer stem cells (CSCs) play an important role in resistance, recurrence as well as metastasis which are factors responsible for the poor survival outcome. In this review, we discuss recent findings regarding cell signaling pathways and markers associated with CSCs and the need to gain a deeper understanding on the properties of CSCs.
Publish Date	2023-05-26 11:17
Citation	Joshi P, Waghmare S. Molecular signaling in cancer stem cells of tongue squamous cell carcinoma: Therapeutic implications and challenges. World J Stem Cells 2023; 15(5): 438-452
URL	https://www.wjgnet.com/1948-0210/full/v15/i5/438.htm
DOI	https://dx.doi.org/10.4252/wjsc.v15.i5.438

Full Article (PDF)	WJSC-15-438.pdf
Full Article (Word)	WJSC-15-438.docx
Manuscript File	82568_Auto_Edited-JLW.docx
Answering Reviewers	82568-Answering reviewers.pdf
Audio Core Tip	82568-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	82568-Conflict-of-interest statement.pdf
Copyright License Agreement	82568-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	82568-Language certificate.pdf
Peer-review Report	82568-Peer-review(s).pdf
Scientific Editor Work List	82568-Scientific editor work list.pdf
CrossCheck Report	82568-CrossCheck report.pdf