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Articles Published Processes
4/13/2023 8:14:59 AM | Browse: 274 | Download: 691
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Received |
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2022-12-23 06:09 |
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Peer-Review Started |
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2022-12-23 06:15 |
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To Make the First Decision |
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Return for Revision |
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2023-01-03 01:39 |
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Revised |
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2023-01-09 06:18 |
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Second Decision |
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2023-03-21 03:07 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-03-21 07:22 |
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Articles in Press |
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2023-03-21 07:22 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-03-27 08:00 |
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Publish the Manuscript Online |
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2023-04-13 08:14 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Challenges in pediatric inherited/metabolic liver disease: Focus on the disease spectrum, diagnosis and management of relatively common disorders
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yi-Gui Zou, Huan Wang, Wen-Wen Li and Dong-Ling Dai |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Shenzhen Science and Technology Innovation Program |
JCYJ20180228175150018 |
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| Corresponding Author |
Dong-Ling Dai, DPhil, MD, PhD, Chief Doctor, Professor, Key Laboratory for Precision Diagnosis and Treatment of Pediatric Digestive System Diseases and Endoscopy Center, Shenzhen Children's Hospital, No. 7019 Yitian Road, Futian District, Shenzhen 518026, Guangdong Province, China. daidong3529@sina.com |
| Key Words |
Hepatitis; Genetic; Liver disease; Cholestasis; Challenge; Pediatric |
| Core Tip |
The spectrum of diseases causing pediatric liver dysfunction has been changing, and an increasing number of inherited/metabolic disorders have been increasingly recognized as major contributors to liver disease in children. Etiological diagnosis remains challenging due to the frequent absence of symptoms or nonspecific signs and limited diagnostic approaches, especially liver biopsy, which is not easily accepted by pediatric patients. Consequently, the treatment of pediatric inherited/metabolic liver disease is challenging. In this manuscript, we review here the challenges in pediatric inherited/metabolic liver disease, including epidemiological changes in the disease spectrum and challenges in etiological diagnosis and treatment. |
| Publish Date |
2023-04-13 08:14 |
| Citation |
Zou YG, Wang H, Li WW, Dai DL. Challenges in pediatric inherited/metabolic liver disease: Focus on the disease spectrum, diagnosis and management of relatively common disorders. World J Gastroenterol 2023; 29(14): 2114-2126 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i14/2114.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i14.2114 |
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