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4/6/2023 10:35:23 AM | Browse: 96 | Download: 197
Publication Name World Journal of Clinical Cases
Manuscript ID 82681
Country China
Received
2022-12-26 11:21
Peer-Review Started
2022-12-26 11:22
To Make the First Decision
Return for Revision
2023-02-08 00:56
Revised
2023-02-23 15:05
Second Decision
2023-03-13 02:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-03-14 03:03
Articles in Press
2023-03-14 03:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-03-15 09:55
Publish the Manuscript Online
2023-04-06 10:35
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Minireviews
Article Title Pyroptosis and its role in cancer
Manuscript Source Unsolicited Manuscript
All Author List Shi-Wei Liu, Wen-Jing Song, Gui-Kai Ma, Hui Wang and Liang Yang
ORCID
Author(s) ORCID Number
Wen-Jing Song http://orcid.org/0000-0003-2583-4362
Liang Yang http://orcid.org/0000-0002-9099-1738
Funding Agency and Grant Number
Corresponding Author Liang Yang, MD, PhD, Chief Physician, Department of Joint Surgery, the Second Hospital of Dalian Medical University, No. 467 Zhongshan Road, Shahekou District, Dalian 116023, Liaoning Province, China. 18863031115@sohu.com
Key Words Pyroptosis; Caspase-1/3/4/5/11; Gasdermin family; Cancer
Core Tip Pyroptosis is a type of inflammatory caspase-dependent programmed cell death mediated by gasdermin proteins, which function in pore formation, cell swelling, and cell membrane rupture. This review discusses the classical and non-classical pathways of pyroptosis and the recent research progress on the molecular mechanisms of pyroptosis. We also review the relationship between various pyroptosis pathway components and different cancers, including nucleotide-binding oligomerization domain-like receptor thermal protein domain associated protein 3 inflammasomes, interleukin (IL)-18, IL-1β, and absent in melanoma 2. The potential applications of this form of cell death as a cancer treatment approach are also explored.
Publish Date 2023-04-06 10:35
Citation Liu SW, Song WJ, Ma GK, Wang H, Yang L. Pyroptosis and its role in cancer. World J Clin Cases 2023; 11(11): 2386-2395
URL https://www.wjgnet.com/2307-8960/full/v11/i11/2386.htm
DOI https://dx.doi.org/10.12998/wjcc.v11.i11.2386
Full Article (PDF) WJCC-11-2386.pdf
Full Article (Word) WJCC-11-2386.docx
Manuscript File 82681_Auto_Edited-LJH-JLW.docx
Answering Reviewers 82681-Answering reviewers.pdf
Audio Core Tip 82681-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 82681-Conflict-of-interest statement.pdf
Copyright License Agreement 82681-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 82681-Language certificate.pdf
Supplementary Material 82681-Supplementary material.pdf
Peer-review Report 82681-Peer-review(s).pdf
Scientific Misconduct Check 82681-Bing-Liu JH-2.jpg
Scientific Misconduct Check 82681-CrossCheck.jpg
Scientific Editor Work List 82681-Scientific editor work list.pdf