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Articles Published Processes
6/15/2023 8:52:34 AM | Browse: 227 | Download: 464
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Received |
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2022-12-26 16:40 |
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Peer-Review Started |
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2022-12-26 16:41 |
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To Make the First Decision |
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Return for Revision |
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2023-02-28 09:07 |
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Revised |
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2023-03-13 18:13 |
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Second Decision |
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2023-04-10 04:04 |
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Accepted by Journal Editor-in-Chief |
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2023-04-16 01:05 |
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Accepted by Executive Editor-in-Chief |
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2023-04-17 08:49 |
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Articles in Press |
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2023-04-17 08:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-06-07 08:11 |
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Publish the Manuscript Online |
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2023-06-15 08:52 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Genetics & Heredity |
| Manuscript Type |
Review |
| Article Title |
Genetics of diabetes
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Shiwali Goyal, Jyoti Rani, Mohd Akbar Bhat and Vanita Vanita |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Vanita Vanita, PhD, Professor, Department of Human Genetics, Guru Nanak Dev University, GT Road, Amritsar 143005, Punjab, India. vanita.humangenetics@gmail.com |
| Key Words |
Type 1 diabetes; Type 2 diabetes; Gestational diabetes mellitus; Maturity-onset diabetes of young; Genome-wide association studies; Common variants; Rare variants |
| Core Tip |
Diabetes pathogenesis encompasses genetic, epigenetic, and environmental variables and their interactions. To date, the examined common variations can explain just a small portion of the heritability of diabetes. Furthermore, the technique of integrating the associated variants as a type of genetic risk score does not accurately predict diabetes risk. As a result, the trend for genetic risk factors for diabetes is shifting from common to rare variants. Aside from genetic variables, systemic data from other transomics such as epigenomics, transcriptomics, proteomics, metabolomics, and metagenomics will contribute to a better understanding of genetic determinants in the progression of metabolic illnesses like diabetes. Technological, computational, and collaborative developments continue to uncover novel genetic diabetes risk factors. There are high prospects for tailored diabetes treatment in the future, based on increased knowledge of the molecular genetic profile of the patients. |
| Publish Date |
2023-06-15 08:52 |
| Citation |
Goyal S, Rani J, Bhat MA, Vanita V. Genetics of diabetes. World J Diabetes 2023; 14(6): 656-679 |
| URL |
https://www.wjgnet.com/1948-9358/full/v14/i6/656.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v14.i6.656 |
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