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Articles Published Processes
4/14/2023 1:45:13 PM | Browse: 359 | Download: 1015
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Received |
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2022-12-29 14:35 |
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Peer-Review Started |
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2022-12-29 14:37 |
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First Decision by Editorial Office Director |
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2023-02-01 06:53 |
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Return for Revision |
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2023-02-01 06:53 |
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Revised |
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2023-02-13 03:10 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2023-03-28 03:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2023-03-29 18:50 |
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Articles in Press |
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2023-03-29 18:50 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-04-10 00:52 |
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Publish the Manuscript Online |
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2023-04-14 13:45 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Mechanisms of gastrointestinal barrier dysfunction in COVID-19 patients
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Weijie Xue, Masaki Honda and Taizo Hibi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Masaki Honda, MD, PhD, Assistant Professor, Department of Transplantation and Pediatric Surgery, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan. honda.masaki@kuh.kumamoto-u.ac.jp |
| Key Words |
Gastrointestinal barrier dysfunction; SARS-CoV-2; COVID-19; Angiotensin-converting enzyme 2; Microbiome; Immune cells |
| Core Tip |
Coronavirus disease 2019 (COVID-19) has become a major global public health event, resulting in a significant social and economic burden. Although COVID-19 was initially characterized as an upper respiratory and pulmonary infection, recent evidence suggests that it is a complex disease including gastrointestinal symptoms. Moreover, it remains unclear whether the gastrointestinal symptoms are caused by direct infection of the gastrointestinal tract by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or are the result of systemic immune activation and subsequent dysregulation of homeostatic mechanisms. This review provides a brief overview of the mechanisms by which SARS-CoV-2 disrupts gastrointestinal barrier integrity. |
| Publish Date |
2023-04-14 13:45 |
| Citation |
Xue W, Honda M, Hibi T. Mechanisms of gastrointestinal barrier dysfunction in COVID-19 patients. World J Gastroenterol 2023; 29(15): 2283-2293 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i15/2283.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i15.2283 |
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