Publication Name	World Journal of Radiology
Manuscript ID	8272
Country	Belgium

Received	2013-12-24 08:52
Peer-Review Started	2013-12-25 09:14
To Make the First Decision	2014-03-12 17:05
Return for Revision	2014-03-21 20:50
Revised	2014-04-22 03:51
Second Decision	2014-07-29 09:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-07-29 09:53
Articles in Press	2014-07-29 09:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-09-22 17:40
Publish the Manuscript Online	2014-09-25 12:08

ISSN	1949-8470 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Topic Highlights
Article Title	From histology to micro-CT: Measuring and modeling resorption cavities and their relation to bone competence
Manuscript Source	Invited Manuscript
All Author List	Jef Vanderoost and G Harry van Lenthe
Funding Agency and Grant Number
Corresponding Author	G Harry van Lenthe, PhD, Biomechanics Section, Department of Mechanical Engineering, KU Leuven, Celestijnenlaan 300c b2419, 3001 Leuven, Belgium. vanlenthe@.kuleuven.be
Key Words	Resorption cavities; Histology; Micro-computed tomography
Core Tip	Osteoclasts create bone deficits by eroding resorption cavities. Understanding how these cavities impair the mechanical quality of the bone is relevant in both in healthy bone and in metabolic bone diseases. However, the current knowledge of their dimensions and effect on bone competence remains limited. Until recently cavity dimensions were estimated from two-dimensional measures (histology), hence, careful interpretation was necessary. With new imaging techniques quantifying resorption cavities in three-dimensional becomes feasible. Computational models have shown that resorption cavities affect bone competence. The use of high-resolution representations and parametric descriptions could improve the quantitative fidelity of these models.
Publish Date	2014-09-25 12:08
Citation	Vanderoost J, van Lenthe GH. From histology to micro-CT: Measuring and modeling resorption cavities and their relation to bone competence. World J Radiol 2014; 6(9): 643-656
URL	http://www.wjgnet.com/1949-8470/full/v6/i9/643.htm
DOI	http://dx.doi.org/10.4329/wjr.v6.i9.643

Full Article (PDF)	WJR-6-643.pdf
Full Article (Word)	WJR-6-643.doc
Manuscript File	8272-Review.doc
Answering Reviewers	8272-Answering reviewers.pdf
Copyright License Agreement	8272-Copyright assignment.pdf
Peer-review Report	8272-Peer review(s).pdf
Scientific Misconduct Check	8272-CrossCheck.jpg
Scientific Editor Work List	8272-Scientific editor work list.pdf