Publication Name	World Journal of Gastroenterology
Manuscript ID	8299
Country	China

Received	2013-12-25 08:39
Peer-Review Started	2013-12-25 12:56
To Make the First Decision	2014-01-09 15:12
Return for Revision	2014-01-17 16:25
Revised	2014-01-21 11:34
Second Decision	2014-03-06 17:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-03-06 18:11
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-17 17:21
Typeset the Manuscript	2014-04-22 09:01
Publish the Manuscript Online	2014-04-29 09:53

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Roles of sphincter of Oddi motility and serum vasoactive intestinal peptide, gastrin and cholecystokinin octapeptide
Manuscript Source	Unsolicited Manuscript
All Author List	Zhen-Hai Zhang, Cheng-Kun Qin, Shuo-Dong Wu, Jian Xu, Xian-Ping Cui, Zhi-Yi Wang and Guo-Zhe Xian
Funding Agency and Grant Number	Funding Agency Grant Number Natural Science Foundation of Shandong Province of China ZR2012HM079
Corresponding Author	Cheng-Kun Qin, PhD, Department of Hepatobiliary Surgery, Shandong Provincial Hospital Affiliated to Shangdong University, 324 Jingwu Road, Jinan 250021, Shandong Province, China. zhangzhenhai410@126.com
Key Words	Pigment gallstone; Sphincter of Oddi; Manometry; Myoelectric activity; Guinea pig; Vasoactive intestinal peptide; Gastrin; Cholecystokinin octapeptide
Core Tip	Biliary stasis is thought to be important in the development of pigment gallstones. Sphincter of Oddi (SO) motility may play an important role in the process of pigment gallstone formation. We used a guinea pig model of pigment gallstones to investigate whether SO dysfunction happens and what a role the sphincter plays in the process of pigment gallstone formation. The myoelectric activity and SO manometry were measured at different stages of stone formation. Pigment gallstone-causing diet may induce SO dysfunction. The disturbance in SO motility may play a role in pigment gallstone formation, and changes in serum vasoactive intestinal peptide and cholecystokinin octapeptide may be important causes of SO dysfunction.
Publish Date	2014-04-29 09:53
Citation	Zhang ZH, Qin CK, Wu SD, Xu J, Cui XP, Wang ZY, Xian GZ. Roles of sphincter of Oddi motility and serum vasoactive intestinal peptide, gastrin and cholecystokinin octapeptide. World J Gastroenterol 2014; 20(16): 4730-4736
URL	http://www.wjgnet.com/1007-9327/full/v20/i16/4730.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i16.4730

Full Article (PDF)	WJG-20-4730.pdf
Full Article (Word)	WJG-20-4730.doc
Manuscript File	8299-Review.doc
Answering Reviewers	8299-Answering reviewers.pdf
Copyright License Agreement	8299-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	8299-Language certificate.PDF
Peer-review Report	8299-Peer reviews.pdf
Scientific Editor Work List	8299-Scientific editor work list.doc