Publication Name	World Journal of Clinical Cases
Manuscript ID	83009
Country	Japan

Received	2023-01-06 09:51
Peer-Review Started	2023-01-06 09:53
To Make the First Decision
Return for Revision	2023-01-30 08:40
Revised	2023-02-20 06:48
Second Decision	2023-03-23 03:15
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-03-23 09:17
Articles in Press	2023-03-23 09:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-04-09 22:11
Publish the Manuscript Online	2023-04-25 23:32

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Reproductive Biology
Manuscript Type	Retrospective Cohort Study
Article Title	Analysis of oxidative stress and antioxidative potential in premature ovarian insufficiency
Manuscript Source	Unsolicited Manuscript
All Author List	Kaoru Kakinuma and Toshiyuki Kakinuma
ORCID	Author(s) ORCID Number Toshiyuki Kakinuma http://orcid.org/0000-0001-7853-4860
Funding Agency and Grant Number
Corresponding Author	Toshiyuki Kakinuma, MD, PhD, Professor, Department of Obstetrics and Gynecology, International Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara 327-2763, Japan. tokakinuma@gmail.com
Key Words	Premature ovarian insufficiency; Reactive oxygen species; Oxidative stress; Ovary; Antioxidant
Core Tip	We hypothesized that oxidative stress, suggested to be a factor in premature ovarian insufficiency (POI) and a potential POI biomarker, is likely a useful target for the treatment and early intervention for various conditions, including early POI diagnosis and infertility treatment. In this retrospective study, we discovered that oxidative stress was significantly higher in patients with POI than in healthy controls, suggesting the use of this measurement as a biomarker of POI.
Publish Date	2023-04-25 23:32
Citation	Kakinuma K, Kakinuma T. Analysis of oxidative stress and antioxidative potential in premature ovarian insufficiency. World J Clin Cases 2023; 11(12): 2684-2693
URL	https://www.wjgnet.com/2307-8960/full/v11/i12/2684.htm
DOI	https://dx.doi.org/10.12998/wjcc.v11.i12.2684

Full Article (PDF)	WJCC-11-2684.pdf
Full Article (Word)	WJCC-11-2684.docx
STROBE Statement	83009-STROBE-Statement-revision.docx
Manuscript File	83009_Auto_Edited-JLW.docx
Answering Reviewers	83009-Answering reviewers.pdf
Audio Core Tip	83009-Audio core tip.mp3
Biostatistics Review Certificate	83009-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	83009-Conflict-of-interest statement.pdf
Copyright License Agreement	83009-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	83009-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	83009-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	83009-Language certificate.pdf
Peer-review Report	83009-Peer-review(s).pdf
Scientific Misconduct Check	83009-Bing-Yan JP-2.png
Scientific Editor Work List	83009-Scientific editor work list.pdf
CrossCheck Report	83009-CrossCheck report.pdf