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Articles Published Processes
8/29/2014 11:57:00 AM | Browse: 1257 | Download: 1243
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Received |
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2013-12-25 09:08 |
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Peer-Review Started |
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2013-12-25 15:05 |
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To Make the First Decision |
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2014-02-14 12:54 |
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Return for Revision |
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2014-02-19 12:29 |
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Revised |
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2014-02-25 04:50 |
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Second Decision |
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2014-05-29 19:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-05-29 19:52 |
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Articles in Press |
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2014-05-29 20:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-08-13 17:23 |
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Publish the Manuscript Online |
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2014-08-29 11:57 |
Category |
Hematology |
Manuscript Type |
Topic Highlights |
Article Title |
Hepatitis C virus and diffuse large B-cell lymphoma: Pathogenesis, behavior and treatment
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Manuscript Source |
Invited Manuscript |
All Author List |
Carlo Visco and Silvia Finotto |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
AViLL/AIL (Associazione Vicentina per le Leucemie, i Linfomi e il Mieloma/Associazione Italiana Leucemie) (Vicenza, Italy) |
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Hematology Project Foundation (HPF, Fondazione Progetto Ematologia, Vicenza, Italy) |
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Corresponding Author |
Correspondence to: Carlo Visco, MD, Department of Hematology and Cell Therapy, San Bortolo Hospital, Ospedale San Bortolo, Via Rodolfi 37, 36100 Vicenza, Italy. carlovisco@hotmail.com |
Key Words |
Hepatitis C virus; Non-Hodgkin lymphoma; Liver; Toxicity; Diffuse large B-cell lymphoma; Rituximab; Cyclophosphamide; Hydroxydaunorubicin; Vincristine; Prednisolone; Immuno-chemotherapy; Antiviral treatment |
Core Tip |
Patients with hepatitis C virus-positive diffuse large B-cell lymphoma should be managed in a multidisciplinary setting. Initial evaluation of liver status and comorbidities is essential to establish if the patient is candidate to curative approaches. Unless contraindicated by adverse clinical conditions, patients should be treated with standard immuno-chemotherapy. Concomitant hepatitis B virus infection and liver failure or cirrhosis confer a significantly higher risk of viral reactivation or therapy related complications. These patients should be managed cautiously and treated with less intense approaches at least for the initial cycles. Antiviral treatment should be considered after the end of immuno-chemotherapy, when lymphoma remission has been achieved. |
Publish Date |
2014-08-29 11:57 |
Citation |
Visco C, Finotto S. Hepatitis C virus and diffuse large B-cell lymphoma: Pathogenesis, behavior and treatment. World J Gastroenterol 2014; 20(32): 11054-11061 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i32/11054.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i32.11054 |
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