Publication Name	World Journal of Stem Cells
Manuscript ID	83125
Country	China

Received	2023-01-08 12:53
Peer-Review Started	2023-01-08 12:54
To Make the First Decision
Return for Revision	2023-02-02 17:08
Revised	2023-02-21 02:11
Second Decision	2023-03-15 03:06
Accepted by Journal Editor-in-Chief	2023-03-16 00:27
Accepted by Executive Editor-in-Chief	2023-03-29 17:18
Articles in Press	2023-03-29 17:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-04-24 06:32
Publish the Manuscript Online	2023-05-26 11:17

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Research & Experimental Medicine
Manuscript Type	Review
Article Title	Stimulating factors for regulation of osteogenic and chondrogenic differentiation of mesenchymal stem cells
Manuscript Source	Invited Manuscript
All Author List	Jia-Qi Zhou, Hao-Yang Wan, Zi-Xuan Wang and Nan Jiang
ORCID	Author(s) ORCID Number Nan Jiang http://orcid.org/0000-0003-2416-1653
Funding Agency and Grant Number
Corresponding Author	Nan Jiang, MD, Researcher, Surgeon, Division of Orthopaedics and Traumatology, Department of Orthopaedics, Nanfang Hospital, Southern Medical University , No.1838 Guangzhou Avenue North, Baiyun District, Guangzhou 510515, Guangdong Province, China. hnxyjn@smu.edu.cn
Key Words	Mesenchymal stem cells; Differentiation; Osteogenic; Chondrogenic; Literature review.
Core Tip	Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating in specific directions. The differentiation process of MSCs depends on diverse specialized external stimulating factors. The results from recent studies have revealed other underrated roles in the differentiation process of MSCs. However, several questions remain to be solved prior to stable and effective clinical treatment. Our review explores the differentiation patterns of MSCs and summarizes the relevant research according to stimulus types. Finally, future prospects are discussed with regard to their clinical applications.
Publish Date	2023-05-26 11:17
Citation	Zhou JQ, Wan HY, Wang ZX, Jiang N. Stimulating factors for regulation of osteogenic and chondrogenic differentiation of mesenchymal stem cells. World J Stem Cells 2023; 15(5): 369-384
URL	https://www.wjgnet.com/1948-0210/full/v15/i5/369.htm
DOI	https://dx.doi.org/10.4252/wjsc.v15.i5.369

Full Article (PDF)	WJSC-15-369.pdf
Full Article (Word)	WJSC-15-369.docx
Manuscript File	83125_Auto_Edited-LM.docx
Answering Reviewers	83125-Answering reviewers.pdf
Audio Core Tip	83125-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	83125-Conflict-of-interest statement.pdf
Copyright License Agreement	83125-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	83125-Language certificate.pdf
Peer-review Report	83125-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	83125-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	83125-Bing-Liu GL-2.png
Scientific Editor Work List	83125-Scientific editor work list.pdf
CrossCheck Report	83125-CrossCheck report.pdf