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Articles Published Processes
5/25/2023 4:10:54 PM | Browse: 228 | Download: 593
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Received |
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2023-01-10 20:46 |
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Peer-Review Started |
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2023-01-10 20:49 |
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To Make the First Decision |
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Return for Revision |
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2023-02-08 01:17 |
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Revised |
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2023-02-26 08:26 |
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Second Decision |
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2023-04-17 03:06 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-04-17 07:50 |
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Articles in Press |
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2023-04-17 07:50 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-04-13 03:12 |
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Typeset the Manuscript |
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2023-05-12 09:03 |
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Publish the Manuscript Online |
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2023-05-25 16:10 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Synchronous manifestation of colorectal cancer and intraductal papillary mucinous neoplasms
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Milko Bozhidarov Mirchev, Irina Boeva, Monika Peshevska-Sekulovska, Veselin Stoitsov and Milena Peruhova |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Milena Peruhova, MD, Assistant Professor, Department of Gastroenterology, Heart and Brain Hospital, Zdrave 1 st, Burgas 8000, Bulgaria. mperuhova@gmail.com |
| Key Words |
Colorectal cancer; Intraductal papillary mucinous neoplasm; Genetic alterations; Extrapancreatic malignancies; Synchronous neoplasms |
| Core Tip |
In this mini-review, we highlighted the genetic alterations that occur in intraductal papillary mucinous neoplasm (IPMN) and colorectal cancer to understand common genetic or epigenetic risk factors that could explain their synchronous manifestation. The process of malignant transformation in both entities is complex, but some distinctive features of IPMN lesions are linked with their genetic heterogeneity. Specific mutations in GNAS and KRAS are mainly expressed in IPMN. A significantly lower frequency of mutations is detected in other cancer-related genes, such as SMAD4, PI3KCA, PTEN, and BRAF. |
| Publish Date |
2023-05-25 16:10 |
| Citation |
Mirchev MB, Boeva I, Peshevska-Sekulovska M, Stoitsov V, Peruhova M. Synchronous manifestation of colorectal cancer and intraductal papillary mucinous neoplasms. World J Clin Cases 2023; 11(15): 3408-3417 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i15/3408.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i15.3408 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
