Publication Name	World Journal of Gastroenterology
Manuscript ID	8323
Country	Japan

Received	2013-12-25 10:11
Peer-Review Started	2013-12-26 09:29
To Make the First Decision	2014-01-09 15:05
Return for Revision	2014-01-17 15:56
Revised	2014-01-28 04:27
Second Decision	2014-03-06 17:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-06 18:10
Articles in Press	2014-05-23 11:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-06-25 11:01
Publish the Manuscript Online	2014-07-14 17:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Autobiography
Article Title	Novel diagnostics for aggravating pancreatic fistulas at the acute phase after pancreatectomy
Manuscript Source	Unsolicited Manuscript
All Author List	Mitsuro Kanda, Tsutomu Fujii, Hideki Takami, Masaya Suenaga, Yoshikuni Inokawa, Suguru Yamada, Daisuke Kobayashi, Chie Tanaka, Hiroyuki Sugimoto, Masahiko Koike, Shuji Nomoto, Michitaka Fujiwara and Yasuhiro Kodera
Funding Agency and Grant Number
Corresponding Author	Tsutomu Fujii, MD, PhD, FACS, Department of Gastroenterological Surgery (Surgery Ⅱ), Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan. fjt@med.nagoya-u.ac.jp
Key Words	Pancreatectomy; Pancreatic fistula; Prediction; Inflammatory marker; C-reactive protein
Core Tip	The diagnostic performance of inflammatory markers and amylase content in drain fluid were compared to identify sensitive predictors of clinically relevant postoperative pancreatic fistulas (POPFs) at the acute phase after pancreatectomy. Receiver operating characteristic curve analyses revealed that the changes in C-reactive protein (CRP) levels from postoperative day (POD) 1 to POD 3 had the greatest area under the curve value for clinically relevant POPFs. Multivariable analyses identified increased elevation of the CRP level as an independent diagnostic factor for clinically relevant POPFs. A steep rise in the CRP level was a highly diagnostic factor for clinically relevant POPFs and may be helpful in selecting the appropriate management for POPFs.
Publish Date	2014-07-14 17:39
Citation	Kanda M, Fujii T, Takami H, Suenaga M, Inokawa Y, Yamada S, Kobayashi D, Tanaka C, Sugimoto H, Koike M, Nomoto S, Fujiwara M, Kodera Y. Novel diagnostics for aggravating pancreatic fistulas at the acute phase after pancreatectomy. World J Gastroenterol 2014; 20(26): 8535-8544
URL	http://www.wjgnet.com/1007-9327/full/v20/i26/8535.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i26.8535

Full Article (PDF)	WJG-20-8535.pdf
Full Article (Word)	WJG-20-8535.doc
Manuscript File	8323-Review.doc
Answering Reviewers	8323-Answering reviewers.pdf
Copyright License Agreement	8323-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	8323-Language certificate.pdf
Peer-review Report	8323-Peer reviews.pdf
Scientific Editor Work List	8323-Scientific editor work list.doc