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5/12/2023 9:13:35 AM | Browse: 150 | Download: 602
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 83231
Country/Territory South Korea
Received
2023-01-13 08:30
Peer-Review Started
2023-01-13 08:32
To Make the First Decision
Return for Revision
2023-01-22 04:26
Revised
2023-02-01 14:43
Second Decision
2023-04-07 01:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-04-07 07:10
Articles in Press
2023-04-07 07:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-05-06 15:30
Publish the Manuscript Online
2023-05-12 09:13
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Acute respiratory distress syndrome and severe pneumonitis after atezolizumab plus bevacizumab for hepatocellular carcinoma treatment: A case report
Manuscript Source Unsolicited Manuscript
All Author List Su Hyeon Cho, Ga Ram You, Chan Park, Sang-Geon Cho, Jong Eun Lee, Sung Kyu Choi, Sung Bum Cho and Jae Hyun Yoon
ORCID
Author(s) ORCID Number
Su Hyeon Cho http://orcid.org/0000-0002-5911-1114
Ga Ram You http://orcid.org/0000-0002-7001-7372
Chan Park http://orcid.org/0000-0002-9838-8757
Sang-Geon Cho http://orcid.org/0000-0002-1373-1887
Jong Eun Lee http://orcid.org/0000-0002-8754-6801
Sung Kyu Choi http://orcid.org/0000-0002-6878-3385
Sung Bum Cho http://orcid.org/0000-0001-9816-3446
Jae Hyun Yoon http://orcid.org/0000-0002-4993-2496
Funding Agency and Grant Number
Funding Agency Grant Number
Chonnam National University Hospital Biomedical Research Institute BCRE22158
Chonnam National University Hospital Biomedical Research Institute NRF-2021R1F1A1061719
Corresponding Author Jae Hyun Yoon, MD, Associate Professor, Department of Gastroenterology and Hepatology, Chonnam National University Hospital and Medical School, Je-bong ro 42, Dong Gu, Gwangju 61469, South Korea. zenmake14@gmail.com
Key Words Hepatocellular carcinoma; Systemic therapy; Adverse events; Pneumonitis; Atezolizumab; Acute respiratory distress syndrome
Core Tip Nowadays, the combination therapy of atezolizumab and bevacizumab is recommended as the first-line systemic treatment for advanced hepatocellular carcinomas. A global phase III study and recent real-world studies demonstrated rare life-threatening adverse events of atezolizumab and bevacizumab. However, our patient underwent acute respiratory distress syndrome and finally died three days after treatment. To the best of our knowledge, this is the first case of severe respiratory failure resulting in death with a very short interval from atezolizumab and bevacizumab administration. Therefore, we suggest close monitoring of lung toxicity after therapy.
Publish Date 2023-05-12 09:13
Citation Cho SH, You GR, Park C, Cho SG, Lee JE, Choi SK, Cho SB, Yoon JH. Acute respiratory distress syndrome and severe pneumonitis after atezolizumab plus bevacizumab for hepatocellular carcinoma treatment: A case report. World J Gastrointest Oncol 2023; 15(5): 892-901
URL https://www.wjgnet.com/1948-5204/full/v15/i5/892.htm
DOI https://dx.doi.org/10.4251/wjgo.v15.i5.892
Full Article (PDF) WJGO-15-892.pdf
Full Article (Word) WJGO-15-892.docx
Manuscript File 83231_Auto_Edited-LJH-JLW.docx
Answering Reviewers 83231-Answering reviewers.pdf
Audio Core Tip 83231-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 83231-Conflict-of-interest statement.pdf
Copyright License Agreement 83231-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 83231-Grant application form(s).pdf
Signed Consent for Treatment Form(s) or Document(s) 83231-Informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 83231-Language certificate.pdf
Peer-review Report 83231-Peer-review(s).pdf
Scientific Misconduct Check 83231-Bing-Liu JH-2.jpg
Scientific Misconduct Check 83231-CrossCheck.png
Scientific Editor Work List 83231-Scientific editor work list.pdf