| Category |
Oncology |
| Manuscript Type |
Prospective Study |
| Article Title |
Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xabier García-Albéniz, Rosa Gallego, Ralf Dieter Hofheinz, Gloria Fernández-Esparrach, Juan Ramón Ayuso-Colella, Josep Antoni Bombí, Carles Conill, Miriam Cuatrecasas, Salvadora Delgado, Angels Ginés, Rosa Miquel, Mario Pagés, Estela Pineda, Verónica Pereira, Aarón Sosa, Oscar Reig, Iván Victoria, Luis Feliz, Antonio María de Lacy, Antoni Castells, Iris Burkholder, Andreas Hochhaus and Joan Maurel |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| “Ajut Josep Font” (Hospital Clinic, Barcelona) |
|
| ASISA fellowship |
to Xabier García-Albéniz |
|
| Corresponding Author |
Xabier García-Albéniz, MD, ScM, Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, United States. xabi@post.harvard.edu |
| Key Words |
Exercise; Follow-up; Gastrointestinal diseases; Irritable bowel syndrome; Physical activity |
| Core Tip |
This study shows that patients with localized rectal cancer can achieve a complete response after preoperative chemoradiation. The inherent good prognosis of these patients will have implications for clinical trial design and care of patients. Withholding adjuvant chemotherapy after complete response following standard neoadjuvant chemoradiotherapy and laparoscopic mesorectal excision might be safe within an experienced multidisciplinary team. |
| Publish Date |
2014-11-17 15:12 |
| Citation |
García-Albéniz X, Gallego R, Hofheinz RD, Fernández-Esparrach G, Ayuso-Colella JR, Bombí JA, Conill C, Cuatrecasas M, Delgado S, Ginés A, Miquel R, Pagés M, Pineda E, Pereira V, Sosa A, Reig O, Victoria I, Feliz L, María de Lacy A, Castells A, Burkholder I, Hochhaus A, Maurel J. Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation. World J Gastroenterol 2014; 20(42): 15820-15829 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i42/15820.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i42.15820 |
