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Articles Published Processes
7/13/2023 8:03:56 AM | Browse: 192 | Download: 561
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Received |
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2023-01-16 06:16 |
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Peer-Review Started |
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2023-01-16 06:18 |
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To Make the First Decision |
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Return for Revision |
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2023-02-08 01:38 |
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Revised |
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2023-02-20 07:01 |
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Second Decision |
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2023-04-10 04:08 |
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Accepted by Journal Editor-in-Chief |
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2023-04-10 04:31 |
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Accepted by Executive Editor-in-Chief |
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2023-04-11 18:16 |
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Articles in Press |
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2023-04-11 18:16 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-05-31 23:56 |
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Typeset the Manuscript |
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2023-07-05 12:11 |
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Publish the Manuscript Online |
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2023-07-13 08:03 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Liver or kidney: Who has the oar in the gluconeogenesis boat and when?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Biswajit Sahoo, Medha Srivastava, Arpit Katiyar, Carolyn Ecelbarger and Swasti Tiwari |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Swasti Tiwari, PhD, Professor, Department of Molecular Medicine and Biotechnology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Mawaiya, Lucknow 226014, India. tiwari.pgi@gmail.com |
| Key Words |
Gluconeogenesis in the kidney and liver; Diabetes; Hormonal regulation; Metabolic acidosis; Insulin resistance; Net glucose metabolism |
| Core Tip |
Both the liver and kidneys are now recognized to have an essential role in regulating glucose homeostasis through gluconeogenesis. However, the two tissue types differ in their preference for substrates. Also, the hormonal regulation of the processes differs in the two tissues. The contribution of kidney vs liver gluconeogenesis may vary under certain physiological and pathological conditions. However, increased gluconeogenesis in both the Liver and kidneys contributes to hyperglycemia in the pathogenic stage of type 2 diabetes mellitus. While in the case of metabolic acidosis, which develops in response to diabetes, gluconeogenesis induction occurs exclusively in the kidneys. Nevertheless, the two organs often compensate for each other by inter-organ coordination to maintain glucose and energy homeostasis. |
| Publish Date |
2023-07-13 08:03 |
| Citation |
Sahoo B, Srivastava M, Katiyar A, Ecelbarger C, Tiwari S. Liver or kidney: Who has the oar in the gluconeogenesis boat and when? World J Diabetes 2023; 14(7): 1049-1056 |
| URL |
https://www.wjgnet.com/1948-9358/full/v14/i7/1049.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v14.i7.1049 |
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