| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Case Report |
| Article Title |
Hemophagocytic lymphohistiocytosis after autologous stem cell transplantation in angioimmunoblastic T-cell lymphoma: A case report
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhi-Rong Zhang, Ai-Xia Dou, Yan Liu, Hong-Bo Zhu, Hai-Peng Jia, Qiu-Hong Kong, Li-Kun Sun and Ai-Qiong Qin |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Jinan Clinical Medical Science and Technology Innovation Plan |
No. 202019141 |
| Norman Bethune Foundation-Feifan Iron Supplement Project |
No. ffbt-C-2022-010 |
|
| Corresponding Author |
Ai-Qiong Qin, MM, Doctor, Doctor, Department of Cadres Medical Care/Gerontology Geriatric, The Second Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, No. 247 Beiyuan street, Jinan 250033, Shandong Province, China. qaqdax20221014@163.com |
| Key Words |
Angioimmunoblastic T-cell lymphoma; Autologous stem cell transplantation; Hemophagocytic lymphohistiocytosis; Complication; Outcome; Immune reconstitution; Case report |
| Core Tip |
Angioimmunoblastic T cell lymphoma (AITL), a subtype of mature peripheral T cell lymphoma, is characterized by intense inflammatory and immune reactions. Although high-dose chemotherapy with autologous stem cell transplantation (ASCT) is currently considered the optimal treatment option for AITL, subsequent development of hemophagocytic lymphohistiocytosis (HLH), a rare, life-threatening immunological syndrome, may still result in poor outcomes. In the present case, we speculate that HLH was likely attributable to immune reconstitution after ASCT. Successful immune reconstitution after ASCT is essential to improving overall survival and preventing opportunistic infections in patients with AITL. |
| Publish Date |
2023-06-12 08:16 |
| Citation |
Zhang ZR, Dou AX, Liu Y, Zhu HB, Jia HP, Kong QH, Sun LK, Qin AQ. Hemophagocytic lymphohistiocytosis after autologous stem cell transplantation in angioimmunoblastic T-cell lymphoma: A case report. World J Clin Cases 2023; 11(17): 4072-4078 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i17/4072.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i17.4072 |
