Publication Name	World Journal of Gastroenterology
Manuscript ID	834
Country	Germany

Received	2012-10-18 09:02
Peer-Review Started	2012-10-18 14:09
To Make the First Decision	2012-11-08 10:53
Return for Revision	2013-02-01 10:15
Revised
Second Decision	2013-04-15 16:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-04-16 07:48
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-07-03 11:43
Publish the Manuscript Online	2013-07-20 20:47

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Endoscopic papillectomy: Data of a prospective observational study
Manuscript Source	Invited Manuscript
All Author List	Uwe Will, Anne-Kathrin Müller, Frank Fueldner, Igor Wanzar and Frank Meyer
Funding Agency and Grant Number
Corresponding Author	Uwe Will, MD, Professor, Department of Gastroenterology, Municipal Hospital, Strasse des Friedens 122, D-07548 Gera, Germany. uwe.will@wkg.srh.de
Key Words	Papilla of Vater; Papillectomy; Endoscopic ultrasonography; Adenoma; Carcinoma; Carcinoid-like tumor; Adenomyomatosis
Core Tip	Taken together, endoscopic ultrasonography is an essential and sufficient diagnostic tool and plays an eminent role in the diagnostic spectrum to preoperatively clarify lesions and diseases of the papilla in conjunction with the competent postinterventional histopathological investigation of a specimen. Endoscopic papillectomy with curative intention is a feasible and safe approach to treat adenomas of the papilla, i.e., it is only reasonable if there is no infiltrating tumor growth. In high-risk patients with carcinoma of the papilla but no hints of deep infiltrating tumor growth, endoscopic papillectomy can be considered a reasonable treatment option with reduced risk and an approximately 80% probability of no recurrence if an R0 resection can be achieved. In patients with jaundice and in case the catheter can not be introduced into the papilla, papillectomy may help to get access to the bile duct to avoid more traumatic surgery. Endoscopic papillectomy is therefore not only used for therapeutic but also for diagnostic purpose. There is a high clinical value of endoscopic papillectomy for well defined indications not only for adenoma but also for carcinoma/neuroendocrine tumor/lymphoma (uT1 and high-risk patient), and adenomyomatosis. Follow-up investigations according to a defined schedule appear to be reasonable including macroscopic assessment, taking a representative biopsy and subsequent histopathological investigation. In addition, continuous systematic investigation of endoscopic papillectomy in daily clinical practice is indicated for the purpose of quality assurance.
Publish Date	2013-07-20 20:47
Citation	Will U, Müller AK, Fueldner F, Wanzar I, Meyer F. Endoscopic papillectomy: Data of a prospective observational study. World J Gastroenterol 2013; 19(27): 4316-4324
URL	http://www.wjgnet.com/1007-9327/full/v19/i27/4316.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i27.4316

Full Article (PDF)	WJG-19-4316.pdf
Manuscript File	834-Review.doc
Answering Reviewers	834-Answering reviewers.pdf
Copyright License Agreement	834-Copyright assignment.pdf
Peer-review Report	834-Peer review.pdf
Scientific Editor Work List	834-Scientific editor work list.doc